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犬空肠蠕动及肠腔内容物转运的餐后模式。

Postprandial patterns of canine jejunal motility and transit of luminal content.

作者信息

Schemann M, Ehrlein H J

出版信息

Gastroenterology. 1986 Apr;90(4):991-1000. doi: 10.1016/0016-5085(86)90878-4.

DOI:10.1016/0016-5085(86)90878-4
PMID:3949125
Abstract

The effects of different nutrient meals and a noncaloric viscous cellulose meal (control) on the motor activity of the canine jejunum were studied. Contraction patterns were detected through six closely spaced, strain-gauge transducers and were analyzed by a computer. Luminal transit was assessed videofluoroscopically. Control meals moved rapidly (1.9 cm/s) along the jejunum. This was achieved by contractions that occurred at a high frequency (12.8 cpm) and propagated over long distances (9.9 cm). In contrast, the transit rates of the nutrient meals were considerably slower (0.5-1.0 cm/s), the frequency of contractions (5.0-8.9 cpm) and the length of spread of contraction waves (2.6-4.8 cm) were decreased, and the incidence of stationary contractions occurring individually or in clusters was increased. A mathematical model incorporating frequency of contractions and the length of their propagation was used to predict the transit of jejunal contents. The results of correlation tests and of the mathematical model revealed that the length of spread of contraction waves was the most important factor that influenced transit.

摘要

研究了不同营养膳食和无热量粘性纤维素膳食(对照)对犬空肠运动活性的影响。通过六个间距紧密的应变片式传感器检测收缩模式,并由计算机进行分析。通过电视荧光透视法评估肠腔转运。对照膳食沿空肠快速移动(1.9厘米/秒)。这是通过高频(12.8次/分钟)发生并远距离传播(9.9厘米)的收缩实现的。相比之下,营养膳食的转运速率明显较慢(0.5 - 1.0厘米/秒),收缩频率(5.0 - 8.9次/分钟)和收缩波传播长度(2.6 - 4.8厘米)降低,单个或成簇出现的静止收缩发生率增加。采用一个结合收缩频率及其传播长度的数学模型来预测空肠内容物的转运。相关性测试和数学模型的结果表明,收缩波传播长度是影响转运的最重要因素。

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