Siegle M L, Ehrlein H J
Institute of Zoophysiology, University of Hohenhein, Stuttgart, Federal Republic of Germany.
Am J Physiol. 1988 Apr;254(4 Pt 1):G552-9. doi: 10.1152/ajpgi.1988.254.4.G552.
In the present study ileal motor patterns caused by orally administered noncaloric and nutrient meals were investigated. Effects of nutrients were additionally elucidated by an ileal infusion of nutrients. Conscious dogs equipped with closely spaced extraluminal transducers were used. Motor patterns were quantified by a computerized method. Transit rates were measured fluoroscopically. Compared with the motor pattern caused by the noncaloric meal, the nutrient meal diminished the number of contractions from 11.7 to 5.9/min, reduced the incidence of contraction waves from 70.8 to 39.4%, shortened the length of contraction spread from 4.0 to 1.4 cm, and slowed the transit rate from 18.4 to 3.2 cm/min. Ileal infusion of nutrients induced a motor pattern similar to that of the nutrient meal. The transit rate correlated with the length of contraction spread (r = 0.75), the ratio between contraction waves and stationary contractions (r = 0.77), and the number of contractions (r = 0.69). The length of contraction spread was the most characteristic feature of motor patterns and the most important factor influencing transit.
在本研究中，对口服无热量餐和营养餐后回肠的运动模式进行了研究。通过回肠输注营养物质进一步阐明了营养物质的作用。使用配备了间距紧密的腔外传感器的清醒犬。运动模式通过计算机化方法进行量化。通过荧光透视法测量转运速率。与无热量餐引起的运动模式相比，营养餐使收缩次数从11.7次/分钟减少至5.9次/分钟，收缩波发生率从70.8%降至39.4%，收缩传播长度从4.0厘米缩短至1.4厘米，转运速率从18.4厘米/分钟减慢至3.2厘米/分钟。回肠输注营养物质诱导出与营养餐相似的运动模式。转运速率与收缩传播长度（r = 0.75）、收缩波与静止收缩的比例（r = 0.77）以及收缩次数（r = 0.69）相关。收缩传播长度是运动模式最具特征的特点，也是影响转运的最重要因素。
