Sirovy Miroslav, Odlozilova Sarka, Kotek Jiri, Zajak Jan, Paral Jiri
University of Defence, Faculty of Military Health Sciences, Department of Military Surgery, Hradec Kralove, Czech Republic; University Hospital and Charles University, Faculty of Medicine, Department of Surgery, Hradec Kralove, Czech Republic.
University of Defence, Faculty of Military Health Sciences, Department of Military Surgery, Hradec Kralove, Czech Republic; University Hospital and Charles University, Faculty of Medicine, Department of Surgery, Hradec Kralove, Czech Republic.
Asian J Surg. 2023 Oct 26. doi: 10.1016/j.asjsur.2023.10.001.
Postoperative adhesions are the most common cause of morbidity after abdominal and pelvic surgery. The clinical manifestations of postoperative adhesions can manifest within a few weeks or even several years after the surgery. They result from peritoneal irritation caused by surgical trauma or intra-abdominal infection. Normal peritoneal healing relies on the balance between fibrin deposition and its degradation. In this paper-using information derived from the Medline, PubMed, and ScienceDirect databases-we briefly summarize the pathogenesis of postoperative intra-abdominal adhesions and various strategies for possible prevention.
术后粘连是腹部和盆腔手术后发病的最常见原因。术后粘连的临床表现可在手术后几周甚至几年内出现。它们是由手术创伤或腹腔内感染引起的腹膜刺激所致。正常的腹膜愈合依赖于纤维蛋白沉积及其降解之间的平衡。在本文中,我们利用从Medline、PubMed和ScienceDirect数据库获得的信息,简要总结了术后腹腔粘连的发病机制以及各种可能的预防策略。