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预防术后腹腔内粘连的现有方法。

Current options for the prevention of postoperative intra-abdominal adhesions.

作者信息

Sirovy Miroslav, Odlozilova Sarka, Kotek Jiri, Zajak Jan, Paral Jiri

机构信息

University of Defence, Faculty of Military Health Sciences, Department of Military Surgery, Hradec Kralove, Czech Republic; University Hospital and Charles University, Faculty of Medicine, Department of Surgery, Hradec Kralove, Czech Republic.

University of Defence, Faculty of Military Health Sciences, Department of Military Surgery, Hradec Kralove, Czech Republic; University Hospital and Charles University, Faculty of Medicine, Department of Surgery, Hradec Kralove, Czech Republic.

出版信息

Asian J Surg. 2023 Oct 26. doi: 10.1016/j.asjsur.2023.10.001.

DOI:10.1016/j.asjsur.2023.10.001
PMID:39492273
Abstract

Postoperative adhesions are the most common cause of morbidity after abdominal and pelvic surgery. The clinical manifestations of postoperative adhesions can manifest within a few weeks or even several years after the surgery. They result from peritoneal irritation caused by surgical trauma or intra-abdominal infection. Normal peritoneal healing relies on the balance between fibrin deposition and its degradation. In this paper-using information derived from the Medline, PubMed, and ScienceDirect databases-we briefly summarize the pathogenesis of postoperative intra-abdominal adhesions and various strategies for possible prevention.

摘要

术后粘连是腹部和盆腔手术后发病的最常见原因。术后粘连的临床表现可在手术后几周甚至几年内出现。它们是由手术创伤或腹腔内感染引起的腹膜刺激所致。正常的腹膜愈合依赖于纤维蛋白沉积及其降解之间的平衡。在本文中,我们利用从Medline、PubMed和ScienceDirect数据库获得的信息,简要总结了术后腹腔粘连的发病机制以及各种可能的预防策略。

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Current options for the prevention of postoperative intra-abdominal adhesions.预防术后腹腔内粘连的现有方法。
Asian J Surg. 2023 Oct 26. doi: 10.1016/j.asjsur.2023.10.001.
2
Pathophysiology and prevention of postoperative peritoneal adhesions.术后腹膜粘连的病理生理学和预防。
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Adhesion prevention in gynaecological surgery.妇科手术中的粘连预防
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Inhibition of cyclooxygenase-2 prevents intra-abdominal adhesions by decreasing activity of peritoneal fibroblasts.抑制环氧化酶-2可通过降低腹膜成纤维细胞的活性来预防腹腔粘连。
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