Rocca Aldo, Aprea Giovanni, Surfaro Giuseppe, Amato Maurizio, Giuliani Antonio, Paccone Marianna, Salzano Andrea, Russo Anna, Tafuri Domenico, Amato Bruno
Department of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, Italy . Via Sergio Pansini, 80131 Naples, Italy.
Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.
Open Med (Wars). 2016 Jun 23;11(1):106-114. doi: 10.1515/med-2016-0021. eCollection 2016.
Intra-abdominal adhesions are the most frequently occurring postoperative complication following abdomino-pelvic surgery. Abdominal and pelvic surgery can lead to peritoneal adhesion formation causing infertility, chronic pelvic pain, and intestinal obstruction. Laparoscopy today is considered the gold standard of care in the treatment of several abdominal pathologies as well as in a wide range of vascular diseases. Laparoscopy has several advantages in comparison to open surgery. These include rapid recovery times, shorter hospitalisation, reduced postoperative pain, as well as cosmetic benefits. The technological improvements in this particular surgical field along with the development of modern techniques and the acquisition of specific laparoscopic skills have allowed for its wider utilization in operations with fully intracorporeal anastomoses. Postoperative adhesions are caused by aberrant peritoneal healing and are the leading cause of postoperative bowel obstruction. The use of anti-adherence barriers is currently being advocated for their prevention. The outcome of the investigation showed adhesion formation inhibition without direct detrimental effects on anastomotic healing. Poor anasto-motic healing can provoke adhesions even in the presence of anti-adhesion barriers. This review gives a short overview on the current evidence on the pathophysiology and prevention of peritoneal adhesions.
腹腔内粘连是腹盆腔手术后最常见的术后并发症。腹部和盆腔手术可导致腹膜粘连形成,从而引起不孕、慢性盆腔疼痛和肠梗阻。如今,腹腔镜检查被认为是治疗多种腹部疾病以及多种血管疾病的金标准。与开放手术相比,腹腔镜检查有多个优点。这些优点包括恢复时间快、住院时间短、术后疼痛减轻以及具有美容效果。这一特定手术领域的技术进步以及现代技术的发展和特定腹腔镜技能的掌握,使得其在完全体内吻合手术中的应用更加广泛。术后粘连是由异常的腹膜愈合引起的,是术后肠梗阻的主要原因。目前主张使用抗粘连屏障来预防粘连。研究结果表明,抗粘连屏障可抑制粘连形成,且对吻合口愈合无直接有害影响。即使存在抗粘连屏障,吻合口愈合不良也可能引发粘连。本综述简要概述了目前关于腹膜粘连病理生理学和预防的证据。