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弗雷德里克·莫氏：皮肤科手术的开拓者。

Frederic Mohs: A Trailblazer in Dermatologic Surgery.

作者信息

Pappas Calista, Demory Michelle L

机构信息

Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.

Microbiology and Immunology, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA.

出版信息

Cureus. 2024 Oct 4;16(10):e70850. doi: 10.7759/cureus.70850. eCollection 2024 Oct.

DOI:10.7759/cureus.70850
PMID:39493035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11531929/
Abstract

Frederic Mohs was an American physician and surgeon who revolutionized the treatment of skin cancer through the development of the Mohs micrographic surgery technique. Born in 1910, Mohs devised this innovative procedure while still a medical student, seeking a more effective method for removing skin cancers with minimal damage to surrounding healthy tissue. The technique, which involves the precise removal of cancerous tissue, layer by layer, while examining each under a microscope, allows for the highest possible cure rates and the preservation of as much healthy tissue as possible. Mohs' method has since become the gold standard in dermatologic surgery for certain types of skin cancer, significantly improving patient outcomes. His contributions have had a lasting impact on both the medical field and the lives of countless patients.

摘要

弗雷德里克·莫氏是一位美国内科医生兼外科医生，他通过开发莫氏显微外科手术技术彻底改变了皮肤癌的治疗方法。莫氏出生于1910年，在还是一名医学生时就设计出了这种创新手术，旨在寻找一种更有效的方法来切除皮肤癌，同时对周围健康组织的损伤最小。该技术需要逐层精确切除癌组织，同时在显微镜下检查每一层，从而实现尽可能高的治愈率，并尽可能保留健康组织。自那以后，莫氏方法已成为某些类型皮肤癌的皮肤科手术黄金标准，显著改善了患者的治疗效果。他的贡献对医学领域和无数患者的生活都产生了持久影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/bafc54435ab4/cureus-0016-00000070850-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/bdf55e7d9d56/cureus-0016-00000070850-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/3da8e3a94df1/cureus-0016-00000070850-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/64286b82078a/cureus-0016-00000070850-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/bafc54435ab4/cureus-0016-00000070850-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/bdf55e7d9d56/cureus-0016-00000070850-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/3da8e3a94df1/cureus-0016-00000070850-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/64286b82078a/cureus-0016-00000070850-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eab5/11531929/bafc54435ab4/cureus-0016-00000070850-i04.jpg

相似文献

1
Frederic Mohs: A Trailblazer in Dermatologic Surgery.弗雷德里克·莫氏：皮肤科手术的开拓者。
Cureus. 2024 Oct 4;16(10):e70850. doi: 10.7759/cureus.70850. eCollection 2024 Oct.
2
Curettage prior to Mohs' micrographic surgery for previously biopsied nonmelanoma skin cancers: what are we curetting? Retrospective, prospective, and comparative study.对于先前已活检的非黑色素瘤皮肤癌，在莫氏显微外科手术前进行刮除术：我们刮除的是什么？一项回顾性、前瞻性和对比性研究。
Dermatol Surg. 2005 Jan;31(1):10-5. doi: 10.1111/j.1524-4725.2005.31001.
3
Mohs micrographic surgery: a review of indications, technique, outcomes, and considerations.Mohs 显微外科手术：适应证、技术、结果及注意事项综述。
An Bras Dermatol. 2021 May-Jun;96(3):263-277. doi: 10.1016/j.abd.2020.10.004. Epub 2021 Mar 24.
4
Mohs Micrographic Surgery for skin cancer.用于皮肤癌的莫氏显微外科手术。
Australas J Dermatol. 1991;32(3):159-64. doi: 10.1111/j.1440-0960.1991.tb01783.x.
5
Frederic E. Mohs, MD, and the history of zinc chloride.医学博士弗雷德里克·E·莫氏与氯化锌的历史
Clin Dermatol. 2018 Jul-Aug;36(4):568-575. doi: 10.1016/j.clindermatol.2017.12.001. Epub 2017 Dec 28.
6
Mohs Micrographic Surgery Appropriate Use Criteria (AUC) Guidelines莫氏显微外科手术合理使用标准（AUC）指南
7
Diagnostic accuracy of autofluorescence-Raman microspectroscopy for surgical margin assessment during Mohs micrographic surgery of basal cell carcinoma.自动荧光拉曼微光谱技术在基底细胞癌 Mohs 显微外科手术中评估手术切缘的诊断准确性。
Br J Dermatol. 2024 Aug 14;191(3):428-436. doi: 10.1093/bjd/ljae196.
8
Optimizing the cut in Mohs' micrographic surgery in regard to skin sparing and microscopic view: is a round incision cut necessary?在皮肤保留和显微镜视野方面优化莫氏显微外科手术的切口：圆形切口有必要吗？
Clin Exp Dermatol. 2005 Mar;30(2):116-9. doi: 10.1111/j.1365-2230.2005.01723.x.
9
Comparative Analysis of Slow Mohs Surgery in Melanoma and Mohs Micrographic Surgery in Squamous Cell Carcinoma and Basal Cell Carcinoma.黑色素瘤中慢速莫氏手术与鳞状细胞癌和基底细胞癌中莫氏显微手术的对比分析
Cureus. 2024 May 5;16(5):e59693. doi: 10.7759/cureus.59693. eCollection 2024 May.
10
[Recurrent acral lentigous melanoma successfully treated with Mohs' micrographic surgery. Case report and review of the literature].[复发性肢端雀斑样痣黑色素瘤经莫氏显微外科手术成功治疗。病例报告及文献综述]
Orv Hetil. 2009 Jun 7;150(23):1071-82. doi: 10.1556/OH.2009.28612.

本文引用的文献

1
Frederic E. Mohs, MD, and the history of zinc chloride.医学博士弗雷德里克·E·莫氏与氯化锌的历史
Clin Dermatol. 2018 Jul-Aug;36(4):568-575. doi: 10.1016/j.clindermatol.2017.12.001. Epub 2017 Dec 28.
2
Frederic Edward Mohs, MD-The Pioneer of Chemosurgery.
JAMA Dermatol. 2017 Jun 1;153(6):522. doi: 10.1001/jamadermatol.2017.0723.
3
Frederic E. Mohs, M.D. (1910-2002): physician and innovator.弗雷德里克·E·莫氏医学博士（1910 - 2002）：医生与创新者。
Am Surg. 2015 May;81(5):433-7. doi: 10.1177/000313481508100520.
4
History of Mohs surgery.Mohs 手术的历史。
Dermatol Clin. 2011 Apr;29(2):135-9, vii. doi: 10.1016/j.det.2011.01.010.
5
The history and evolution of Mohs micrographic surgery.莫氏显微外科手术的历史与演变
Dermatol Surg. 2000 Apr;26(4):303-7. doi: 10.1046/j.1524-4725.2000.00504.x.
6
Chemosurgery.化学外科手术
Clin Plast Surg. 1980 Jul;7(3):349-60.
7
Mohs micrographic surgery. A historical perspective.莫氏显微外科手术：历史视角
Dermatol Clin. 1989 Oct;7(4):609-11.