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脐疝修补术中偶然发现无症状的低度黏液性阑尾肿瘤:一例强调术中警惕性的病例报告

Incidental discovery of asymptomatic low-grade mucinous appendiceal tumor during paraumbilical hernia repair: A case report emphasizing intraoperative vigilance.

作者信息

Alkheder Ahmad, Fathallah Ibrahim, Alajrd Abd Alrhman, Alsodi Zeina, Rahal Majed Abdul Karim

机构信息

Department of Otorhinolaryngology, Al Mouwasat University Hospital, Faculty of Medicine, Damascus University, Damascus, Syria; Faculty of Medicine, Syrian Private University, Damascus, Syria; Faculty of Medicine, Damascus University, Damascus, Syria.

Faculty of Medicine, Al-Baath University, Homs, Syria.

出版信息

Int J Surg Case Rep. 2024 Oct;123:110329. doi: 10.1016/j.ijscr.2024.110329. Epub 2024 Sep 21.

Abstract

INTRODUCTION

Mucinous appendiceal tumor is an exceptionally rare and indolent epithelial neoplasm characterized by the production of mucin within the appendix. Here we present a rare case of a large, asymptomatic mucinous appendiceal tumor discovered incidentally during repair of a paraumbilical hernia.

CASE PRESENTATION

A 73-year-old man with a complex medical history presented with epigastric pain, nausea, vomiting, and constipation. Diagnosed with a strangulated paraumbilical hernia. During hernia repair surgery, a low-grade mucinous appendiceal tumor was accidentally discovered. Post-operative monitoring over 18 months, including colonoscopy and CT scans, showed no recurrence.

DISCUSSION

Appendiceal primary tumors, though rare, can originate from neuroendocrine or epithelial cells. Epithelial tumors, including mucinous adenocarcinoma, produce mucin, potentially leading to pseudomyxoma peritonei, characterized by mucinous ascites and abdominal swelling. These tumors are often incidentally discovered during surgery, as symptoms are nonspecific, resembling acute appendicitis or causing abdominal distension. Diagnosis requires histopathology, revealing mucin accumulation and irregular glandular structures. Treatment typically involves cytoreductive surgery with hyperthermic intraperitoneal chemotherapy to manage the condition effectively.

CONCLUSION

This case emphasizes the critical need for intraoperative vigilance and histopathological analysis in detecting appendiceal mucinous tumors during abdominal surgery, ensuring accurate diagnosis and favorable outcomes.

摘要

引言

黏液性阑尾肿瘤是一种极为罕见且生长缓慢的上皮性肿瘤,其特征是阑尾内产生黏液。在此,我们报告一例罕见的大型无症状黏液性阑尾肿瘤,该肿瘤在脐旁疝修补术中偶然发现。

病例介绍

一名有复杂病史的73岁男性,出现上腹部疼痛、恶心、呕吐和便秘症状。诊断为绞窄性脐旁疝。在疝修补手术中,意外发现了一个低级别黏液性阑尾肿瘤。术后18个月的监测,包括结肠镜检查和CT扫描,均未显示复发迹象。

讨论

阑尾原发性肿瘤虽然罕见,但可起源于神经内分泌或上皮细胞。上皮性肿瘤,包括黏液性腺癌,会产生黏液,可能导致腹膜假黏液瘤,其特征为黏液性腹水和腹部肿胀。这些肿瘤通常在手术中偶然发现,因为症状不具特异性,类似急性阑尾炎或导致腹部膨胀。诊断需要组织病理学检查,以揭示黏液积聚和不规则腺结构。治疗通常包括减瘤手术及术中腹腔内热灌注化疗,以有效控制病情。

结论

本病例强调了在腹部手术中检测阑尾黏液性肿瘤时,术中保持警惕和进行组织病理学分析的迫切需求,以确保准确诊断和良好预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7868/11440772/13293e35bd7e/gr1.jpg

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