Su Bin Brenda, Blackmon Warren, Xu Chun, Holt Christopher, Boateng Nathaniel, Wang Darren, Szafron Vibha, Anagnostou Aikaterini, Anvari Sara, Davis Carla M
Immunology, Allergy, and Retrovirology Division of the Department of Pediatrics at Baylor College of Medicine, William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston, TX, United States.
Department of Health and Biomedical Sciences at the University of Texas Rio Grande Valley, One West University Blvd, Brownsville, TX, United States.
Front Allergy. 2024 Oct 18;5:1456999. doi: 10.3389/falgy.2024.1456999. eCollection 2024.
Shrimp allergy, the most common food allergy in the United States, affects up to 2% of the population. Its etiology is multi-factorial with the combination of genetic predisposition and environmental exposures. This review summarizes the latest diagnosis and management strategies for shrimp allergy. Currently, the double-blind, placebo-controlled food challenge is the gold standard for diagnosis. Moreover, mainstream and experimental management strategies include food allergen avoidance, the FDA-approved omalizumab, and oral immunotherapy. Herein, we emphasize the urgent need to develop more effective diagnostic tools and therapies for shrimp allergy.
虾过敏是美国最常见的食物过敏，影响着多达2%的人口。其病因是多因素的，由遗传易感性和环境暴露共同作用所致。本综述总结了虾过敏的最新诊断和管理策略。目前，双盲、安慰剂对照食物激发试验是诊断的金标准。此外，主流和试验性管理策略包括避免食物过敏原、美国食品药品监督管理局批准的奥马珠单抗以及口服免疫疗法。在此，我们强调迫切需要开发更有效的虾过敏诊断工具和治疗方法。
