检测小鼠血清及一名创伤弧菌病康复者血清中的抗创伤弧菌溶血素抗体。
Detection of anti-Vibrio vulnificus cytolysin antibodies in sera from mice and a human surviving V. vulnificus disease.
作者信息
Gray L D, Kreger A S
出版信息
Infect Immun. 1986 Mar;51(3):964-5. doi: 10.1128/iai.51.3.964-965.1986.
Abstract
An enzyme-linked immunosorbent assay and a cytolysin neutralization assay were used detect anti-Vibrio vulnificus cytolysin antibodies in sera from mice and a human that survived V. vulnificus disease. The detection of antibodies against the cytolysin indicated that the cytolysin is produced in vivo, and this observation is consistent with the hypothesis that the cytolysin is involved in the pathogenesis of V. vulnificus disease.
摘要
采用酶联免疫吸附测定法和溶细胞素中和测定法，检测了患创伤弧菌病后存活的小鼠和人的血清中抗创伤弧菌溶细胞素抗体。针对溶细胞素的抗体检测表明，溶细胞素在体内产生，这一观察结果与溶细胞素参与创伤弧菌病发病机制的假说一致。
相似文献
1
Detection of anti-Vibrio vulnificus cytolysin antibodies in sera from mice and a human surviving V. vulnificus disease.检测小鼠血清及一名创伤弧菌病康复者血清中的抗创伤弧菌溶血素抗体。
Infect Immun. 1986 Mar;51(3):964-5. doi: 10.1128/iai.51.3.964-965.1986.
2
Detection of Vibrio vulnificus cytolysin in V. vulnificus-infected mice.
Toxicon. 1989;27(4):439-64. doi: 10.1016/0041-0101(89)90208-0.
3
The extracellular cytolysin of Vibrio vulnificus: inactivation and relationship to virulence in mice.
Infect Immun. 1991 Jan;59(1):192-7. doi: 10.1128/iai.59.1.192-197.1991.
4
Capsular polysaccharide-protein conjugate vaccines of carbotype 1 Vibrio vulnificus: construction, immunogenicity, and protective efficacy in a murine model.1型创伤弧菌荚膜多糖-蛋白结合疫苗：在小鼠模型中的构建、免疫原性及保护效力
Infect Immun. 1995 Aug;63(8):2906-11. doi: 10.1128/iai.63.8.2906-2911.1995.
5
Cytotoxic mechanism of Vibrio vulnificus cytolysin in CPAE cells.
Life Sci. 2002 Mar 8;70(16):1923-34. doi: 10.1016/s0024-3205(02)01480-7.
6
Identification of Vibrio vulnificus O serovars with antilipopolysaccharide monoclonal antibody.用抗脂多糖单克隆抗体鉴定创伤弧菌O血清型
J Clin Microbiol. 1991 Aug;29(8):1684-8. doi: 10.1128/jcm.29.8.1684-1688.1991.
7
Pulmonary damage by Vibrio vulnificus cytolysin.创伤弧菌溶血素对肺部的损伤
Infect Immun. 1996 Jul;64(7):2873-6. doi: 10.1128/iai.64.7.2873-2876.1996.
8
Vibrio vulnificus cytolysin induces inflammatory responses in RAW264.7 macrophages through calcium signaling and causes inflammation in vivo.创伤弧菌细胞溶素通过钙信号诱导 RAW264.7 巨噬细胞发生炎症反应，并在体内引起炎症。
Microb Pathog. 2019 Dec;137:103789. doi: 10.1016/j.micpath.2019.103789. Epub 2019 Oct 9.
9
Coagglutination of Vibrio cholerae, Vibrio mimicus, and Vibrio vulnificus with anti-flagellar monoclonal antibody.霍乱弧菌、拟态弧菌和创伤弧菌与抗鞭毛单克隆抗体的协同凝集反应。
J Clin Microbiol. 1988 Oct;26(10):1962-6. doi: 10.1128/jcm.26.10.1962-1966.1988.
10
Antibodies that react with the capsular polysaccharide of Vibrio vulnificus are detectable in infected patients, and in persons without known exposure to the organism.
Diagn Microbiol Infect Dis. 1996 Mar;24(3):165-7. doi: 10.1016/0732-8893(96)00020-x.
引用本文的文献
1
Protective effect of polygoni cuspidati radix and emodin on Vibrio vulnificus cytotoxicity and infection.虎杖及大黄素对创伤弧菌细胞毒性和感染的保护作用。
J Microbiol. 2008 Dec;46(6):737-43. doi: 10.1007/s12275-008-0232-x. Epub 2008 Dec 24.
2
A calcium-calmodulin antagonist blocks experimental Vibrio vulnificus cytolysin-induced lethality in an experimental mouse model.一种钙调蛋白拮抗剂在实验性小鼠模型中可阻断实验性创伤弧菌溶细胞素诱导的致死作用。
Infect Immun. 2004 Oct;72(10):6157-9. doi: 10.1128/IAI.72.10.6157-6159.2004.
3
Isolation and characterization of a Vibrio vulnificus mutant deficient in both extracellular metalloprotease and cytolysin.一种同时缺乏细胞外金属蛋白酶和细胞毒素的创伤弧菌突变体的分离与鉴定
Infect Immun. 2001 Sep;69(9):5943-8. doi: 10.1128/IAI.69.9.5943-5948.2001.
4
Pathogenesis of infection by clinical and environmental strains of Vibrio vulnificus in iron-dextran-treated mice.右旋糖酐铁处理小鼠中临床和环境创伤弧菌菌株感染的发病机制
Infect Immun. 2000 Oct;68(10):5785-93. doi: 10.1128/IAI.68.10.5785-5793.2000.
5
Capsular polysaccharide-protein conjugate vaccines of carbotype 1 Vibrio vulnificus: construction, immunogenicity, and protective efficacy in a murine model.1型创伤弧菌荚膜多糖-蛋白结合疫苗：在小鼠模型中的构建、免疫原性及保护效力
Infect Immun. 1995 Aug;63(8):2906-11. doi: 10.1128/iai.63.8.2906-2911.1995.
6
Marker exchange mutagenesis of the aerolysin determinant in Aeromonas hydrophila demonstrates the role of aerolysin in A. hydrophila-associated systemic infections.嗜水气单胞菌气溶素决定簇的标记交换诱变证明了气溶素在嗜水气单胞菌相关全身感染中的作用。
Infect Immun. 1987 Sep;55(9):2274-80. doi: 10.1128/iai.55.9.2274-2280.1987.
本文引用的文献
1
Edema and hemoconcentration in mice experimentally infected with Vibrio vulnificus.实验感染创伤弧菌的小鼠出现水肿和血液浓缩。
Infect Immun. 1981 Jun;32(3):1193-9. doi: 10.1128/iai.32.3.1193-1199.1981.
2
Detection of extracellular toxin(s) produced by Vibrio vulnificus.创伤弧菌产生的细胞外毒素的检测
Infect Immun. 1981 Aug;33(2):583-90. doi: 10.1128/iai.33.2.583-590.1981.
3
Diseases of humans (other than cholera) caused by vibrios.由弧菌引起的人类疾病（霍乱除外）。
Annu Rev Microbiol. 1980;34:341-67. doi: 10.1146/annurev.mi.34.100180.002013.
4
Vibrio vulnificus infection. Case report and update since 1970.创伤弧菌感染。病例报告及自1970年以来的最新情况。
J Am Acad Dermatol. 1983 Aug;9(2):243-51. doi: 10.1016/s0190-9622(83)80357-0.
5
Streptococcal growth and toxin production in vivo.链球菌在体内的生长及毒素产生
Infect Immun. 1983 May;40(2):501-5. doi: 10.1128/iai.40.2.501-505.1983.
6
Detection by enzyme-linked immunosorbent assays of antibody specific for Pseudomonas proteases and exotoxin A in sera from cystic fibrosis patients.通过酶联免疫吸附测定法检测囊性纤维化患者血清中针对铜绿假单胞菌蛋白酶和外毒素A的特异性抗体。
J Clin Microbiol. 1982 Jun;15(6):1054-8. doi: 10.1128/jcm.15.6.1054-1058.1982.
7
Cytolytic activity and virulence of Vibrio damsela.美人鱼弧菌的细胞溶解活性和毒力
Infect Immun. 1984 May;44(2):326-31. doi: 10.1128/iai.44.2.326-331.1984.
8
Protection of mice against Vibrio vulnificus disease by vaccination with surface antigen preparations and anti-surface antigen antisera.通过接种表面抗原制剂和抗表面抗原抗血清保护小鼠免受创伤弧菌病侵害。
Infect Immun. 1984 Sep;45(3):537-43. doi: 10.1128/iai.45.3.537-543.1984.
9
Vibrio species of medical importance.
Diagn Microbiol Infect Dis. 1984 Sep;2(4):263-76. doi: 10.1016/0732-8893(84)90057-9.
10
Serum antibodies to heat-labile enterotoxin of Campylobacter jejuni.空肠弯曲菌不耐热肠毒素的血清抗体。
J Infect Dis. 1985 Aug;152(2):413-6. doi: 10.1093/infdis/152.2.413.
Zotero 插件