Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Department of Political Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Front Public Health. 2024 Oct 18;12:1365744. doi: 10.3389/fpubh.2024.1365744. eCollection 2024.
The COVID-19 comorbid population is at higher risk of developing severe health issues like acute respiratory distress syndrome, coagulation syndrome, metabolic acidosis, and septic shock, potentially leading to patient death. Patients' knowledge, attitudes, and practices (KAP) significantly influence their response to the pandemic and aid in enhancing health policy implementation.
To identify and evaluate the pattern and associated factors to COVID-19 knowledge, attitude, and practice among individuals with comorbidities.
The systematic review followed the PRISMA guidelines. Relevant studies assessing the KAP of comorbid patients were retrieved by carefully searching the PubMed and Google Scholar databases. The appraisal tool for cross-sectional studies was used to determine the quality of the included studies and the risk of biases.
Eighteen studies met the inclusion criteria and were included in the review. The pooled sample size of the included studies was 9,104. Different comorbidities reported in the studies include hypertension, diabetes, psychological disorders, and cancer. Pooled analysis showed that 65% of patients showed good knowledge, 57% of patients showed a positive attitude and 51% of patients followed good practices to manage the COVID-19 in presence of their comorbid condition. Significant factors impacting knowledge, attitude and practice in COVID-19 comorbid patients were ethnicity OR 1.78 [95% CI 1.35-2.32]; educational status 3.2 [2.79-3.58]; urban residence 2.43 [1.65-3.02]; employment Status 1.67[1.34-2.12]; financial Status 4.02[3.66-4.38]; occupation 3.65[3.31-4.25]; information Source 2.64[2.19-3.26]; comorbidity 3.28[2.78-3.61]; and duration of chronic illness 1.59[1.31-2.04].
Comorbid COVID-19 patients showed good knowledge, positive attitude and good practice towards the management of the disease.
COVID-19 合并症患者患急性呼吸窘迫综合征、凝血综合征、代谢性酸中毒和感染性休克等严重健康问题的风险更高，可能导致患者死亡。患者的知识、态度和行为（KAP）对他们对大流行的反应有重大影响，并有助于加强卫生政策的实施。
确定和评估合并症患者 COVID-19 知识、态度和行为的模式和相关因素。
系统综述遵循 PRISMA 指南。通过仔细搜索 PubMed 和 Google Scholar 数据库，检索评估合并症患者 KAP 的相关研究。使用横断面研究评估工具来确定纳入研究的质量和偏倚风险。
符合纳入标准并纳入综述的研究有 18 项。纳入研究的汇总样本量为 9104 例。研究中报告的不同合并症包括高血压、糖尿病、心理障碍和癌症。汇总分析显示，65%的患者具有良好的知识，57%的患者具有积极的态度，51%的患者在合并症存在的情况下遵循良好的实践来管理 COVID-19。影响 COVID-19 合并症患者知识、态度和行为的重要因素包括种族 OR 1.78[95%CI 1.35-2.32]；教育程度 3.2[2.79-3.58]；城市居住 2.43[1.65-3.02]；就业状况 1.67[1.34-2.12]；财务状况 4.02[3.66-4.38]；职业 3.65[3.31-4.25]；信息来源 2.64[2.19-3.26]；合并症 3.28[2.78-3.61]；以及慢性疾病持续时间 1.59[1.31-2.04]。
COVID-19 合并症患者对疾病的管理表现出良好的知识、积极的态度和良好的实践。
