Chervenkov Lyubomir, Georgiev Aleksandar, Doykov Mladen, Velikova Tsvetelina
Department of Diagnostic Imaging, Medical University Plovdiv, Plovdiv 4000, Bulgaria.
Research Complex for Translational Neuroscience, Medical University of Plovdiv, Plovdiv 4002, Bulgaria.
World J Radiol. 2024 Oct 28;16(10):528-536. doi: 10.4329/wjr.v16.i10.528.
Breast cancer morbidity has been increasing worldwide, but treatments are improving. The therapeutic response depends on the stage at which the disease is diagnosed. Therefore, early diagnosis has never been more essential for successful treatment and a reduction in mortality rates. Radiology plays a pivotal role in cancer detection, and advances in ultrasound (US) palpation have shown promising results for breast cancer imaging. The addition of two-dimensional-shear wave elastography (2D-SWE) US in the routine breast imaging exam can increase early cancer detection and promote better surveillance.
To evaluate the clinical applications of 2D-SWE US in breast cancer detection and its combination with other imaging modalities.
The 200 consecutive female patients aged 50-80 were examined to evaluate palpable breast lesions. All patients underwent mammography, bright mode (B-mode) US, and 2D-SWE followed by US-guided biopsy in two consecutive sessions.
Combining B-mode and shear wave US imaging with X-ray mammography revealed 100% of the suspicious lesions, resulting in greater sensitivity, specificity, and negative predictive value. The result improves compared to either B-mode or 2D-SWE alone ( = 0.02).
Combining 2D-SWE with conventional US and X-ray techniques improves the chance of early cancer detection. Including 2D-SWE in regular breast imaging routines can reduce the need for biopsies and improve the chance of early cancer detection and survivability with the proper line of therapy.
乳腺癌发病率在全球范围内一直在上升，但治疗方法也在不断改进。治疗反应取决于疾病被诊断时的阶段。因此，早期诊断对于成功治疗和降低死亡率至关重要。放射学在癌症检测中起着关键作用，超声（US）触诊技术的进步在乳腺癌成像方面已显示出有前景的结果。在常规乳腺成像检查中加入二维剪切波弹性成像（2D-SWE）超声可以提高早期癌症检测率并促进更好的监测。
评估2D-SWE超声在乳腺癌检测中的临床应用及其与其他成像方式联合应用的情况。
对200名年龄在50至80岁之间的连续女性患者进行检查，以评估可触及的乳腺病变。所有患者均接受了乳房X线摄影、明亮模式（B模式）超声和2D-SWE检查，随后在连续两个疗程中接受超声引导下活检。
将B模式和剪切波超声成像与乳房X线摄影相结合可发现100%的可疑病变，从而具有更高的敏感性、特异性和阴性预测值。与单独使用B模式或2D-SWE相比，结果有所改善（P = 0.02）。
将2D-SWE与传统超声和X线技术相结合可提高早期癌症检测几率。在常规乳腺成像程序中纳入2D-SWE可以减少活检需求，并通过适当的治疗方案提高早期癌症检测几率和生存率。
