Li Mixia, Huang Maoxun, Piao Hulin, Wang Yong, Liu Kexiang
Department of Cardiovascular Surgery, The Second Hospital of Jilin University, Changchun, China.
Front Cardiovasc Med. 2024 Oct 18;11:1437903. doi: 10.3389/fcvm.2024.1437903. eCollection 2024.
Primary cardiac synovial sarcoma (PCSS) is a rare and highly aggressive tumor with a significant mortality rate. Treatment guidelines have not been defined given the relative rarity of the condition, especially for pregnant women. Described herein is a 36-year-old pregnant woman at 29 weeks with gestation who was hospitalized due to chest tightness and nausea, and echocardiography found a mass involved in the right heart and the tricuspid valve. She had to undergo cardiac surgery because the mass almost blocked the opening of the tricuspid valve. She underwent a radical resection of the masses and tricuspid valve, followed by replacement of the tricuspid valve with a mechanical valve. She successfully delivered a healthy baby boy. The diagnosis of synovial sarcoma is confirmed by positive results indicating rearrangement of the SYT gene. The patient survived throughout the 30-month follow-up period. There are no reported cases of pregnant women diagnosed with cardiac synovial sarcoma and have undergone cardiac surgery and cesarean section. Our treatment plan not only maximizes patient survival but also ensures fetal survival. This situation is rare and needs documentation.
原发性心脏滑膜肉瘤（PCSS）是一种罕见且侵袭性很强的肿瘤，死亡率很高。鉴于这种疾病相对罕见，尤其是在孕妇中，尚未制定治疗指南。本文描述了一名36岁、孕29周的孕妇，因胸闷和恶心入院，超声心动图发现右心和三尖瓣有肿物。由于肿物几乎阻塞了三尖瓣开口，她不得不接受心脏手术。她接受了肿物和三尖瓣的根治性切除，随后用机械瓣膜置换了三尖瓣。她成功产下一名健康男婴。SYT基因重排阳性结果证实为滑膜肉瘤。患者在30个月的随访期内均存活。尚无孕妇被诊断为心脏滑膜肉瘤并接受心脏手术和剖宫产的报道。我们的治疗方案不仅使患者生存率最大化，还确保了胎儿存活。这种情况很罕见，需要记录在案。
