糖尿病足骨髓炎患者中具有利福平药物相互作用的药物高处方率：利福布汀是否应纳入辅助治疗的临床试验？
High Prescription Rate of Medications With Rifampin Drug-drug Interactions in Patients With Diabetic Foot Osteomyelitis: Should Rifabutin Be Included in Clinical Trials for Adjunctive Therapy?
作者信息
Mallarino-Haeger Christina, Watson Allison, Mahgoub Umnia, Francis Lily, Heydari Maryam, Choudhary Muaaz, Garcia-Toca Manuel, Patel Manish, Kempker Russell R, Fayfman Maya, Schechter Marcos C
机构信息
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
出版信息
Open Forum Infect Dis. 2024 Oct 11;11(11):ofae582. doi: 10.1093/ofid/ofae582. eCollection 2024 Nov.
Abstract
Rifampin may improve diabetic foot osteomyelitis outcomes, but its extensive drug-drug interactions could hamper its use. Here, through a review of the medications prescribed to a cohort of 190 persons with diabetic foot osteomyelitis, we show that rifabutin, a rifamycin with fewer drug-drug interactions, would be easier to implement in practice.
摘要
利福平可能会改善糖尿病足骨髓炎的治疗效果，但其广泛的药物相互作用可能会妨碍其使用。在此，通过回顾190例糖尿病足骨髓炎患者所开具的药物，我们发现利福布汀（一种药物相互作用较少的利福霉素）在实际应用中更易于实施。
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High Prescription Rate of Medications With Rifampin Drug-drug Interactions in Patients With Diabetic Foot Osteomyelitis: Should Rifabutin Be Included in Clinical Trials for Adjunctive Therapy?糖尿病足骨髓炎患者中具有利福平药物相互作用的药物高处方率：利福布汀是否应纳入辅助治疗的临床试验？
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The intersocietal IWGDF, ESVS, SVS guidelines on peripheral artery disease in people with diabetes mellitus and a foot ulcer.国际血管生成学会（IWGDF）、欧洲血管外科学会（ESVS）、血管外科学会（SVS）关于糖尿病足溃疡患者外周动脉疾病的指南。
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