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How to survive enormous amounts of alcohol.

作者信息

Spanagel Rainer

机构信息

Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim D-68159, Germany.

出版信息

Proc Natl Acad Sci U S A. 2024 Nov 12;121(46):e2420068121. doi: 10.1073/pnas.2420068121. Epub 2024 Nov 4.

DOI:10.1073/pnas.2420068121
PMID:39495934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11573529/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/349b/11573529/6fe8c1c90d52/pnas.2420068121fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/349b/11573529/6fe8c1c90d52/pnas.2420068121fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/349b/11573529/6fe8c1c90d52/pnas.2420068121fig01.jpg

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本文引用的文献

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Tolerance and efficient metabolization of extremely high ethanol concentrations by a social wasp.一种社会性黄蜂对极高浓度乙醇的耐受性和高效代谢。
Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2410874121. doi: 10.1073/pnas.2410874121. Epub 2024 Oct 21.
2
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.多血统个体超过 100 万人的问题性饮酒使用的遗传学研究。
Nat Med. 2023 Dec;29(12):3184-3192. doi: 10.1038/s41591-023-02653-5. Epub 2023 Dec 7.
3
Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis.
酒精使用障碍的药物治疗:系统评价和荟萃分析。
JAMA. 2023 Nov 7;330(17):1653-1665. doi: 10.1001/jama.2023.19761.
4
Genetic diversity fuels gene discovery for tobacco and alcohol use.遗传多样性为烟草和酒精使用的基因发现提供了动力。
Nature. 2022 Dec;612(7941):720-724. doi: 10.1038/s41586-022-05477-4. Epub 2022 Dec 7.
5
Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review.醇脱氢酶、醛脱氢酶与酒精使用障碍:批判性回顾
Alcohol Clin Exp Res. 2018 Dec;42(12):2281-2297. doi: 10.1111/acer.13904. Epub 2018 Nov 11.
6
Alcohol dependence and very high risk level of alcohol consumption: a life-threatening and debilitating disease.酒精依赖和极高的酒精消费水平:危及生命和使人虚弱的疾病。
Addict Biol. 2018 Jul;23(4):961-968. doi: 10.1111/adb.12646.
7
Modeling of Human Hepatic and Gastrointestinal Ethanol Metabolism with Kinetic-Mechanism-Based Full-Rate Equations of the Component Alcohol Dehydrogenase Isozymes and Allozymes.基于动力学机制的全速率方程对人类肝脏和胃肠道乙醇代谢的建模:组成型醇脱氢酶同工酶和同种异型的作用。
Chem Res Toxicol. 2018 Jul 16;31(7):556-569. doi: 10.1021/acs.chemrestox.8b00003. Epub 2018 Jul 5.
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Ethanol metabolites: their role in the assessment of alcohol intake.乙醇代谢产物:它们在酒精摄入量评估中的作用。
Alcohol Clin Exp Res. 2015 Nov;39(11):2060-72. doi: 10.1111/acer.12851. Epub 2015 Sep 7.
9
The heritability of alcohol use disorders: a meta-analysis of twin and adoption studies.酒精使用障碍的遗传度:双生子和收养研究的荟萃分析
Psychol Med. 2015 Apr;45(5):1061-72. doi: 10.1017/S0033291714002165. Epub 2014 Aug 29.
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PLoS One. 2012;7(3):e32677. doi: 10.1371/journal.pone.0032677. Epub 2012 Mar 9.