Chinese Medical College, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Medicine (Baltimore). 2024 Nov 1;103(44):e40235. doi: 10.1097/MD.0000000000040235.
This review aimed to evaluate the effectiveness and safety of Baduanjin qigong on perimenopausal and postmenopausal symptoms based on clinical trials. A literature search was conducted in 7 databases up to June 30, 2023. The information of study design and observed indicator based on perimenopausal and postmenopausal stage was extracted. We mainly analyzed the effectiveness, safety and the methodology quality. Thirty-five trials were selected, and 17 original studies were considered good methodological quality. During perimenopause, Baduanjin was mainly to treat mood disorders (63.64%, 14/22), among which 6 (42.86%, 6/14) were depression, 2 (14.29%, 2/14) were depression and anxiety, and 1 (7.14%, 1/14) was anxiety, as well as 5 (35.71%, 5/14) sleep disorders. And the exercise program had a duration of 45 to 50 minutes (57.14%, 8/14), 7 times (71.43%, 10/14) a week. The programs lasting 3 months (42.86%, 6/14), accounted for the highest proportion of the exercise program. In the postmenopausal stage, Baduanjin was used to treat osteoporosis (84.62%, 11/13). From the data available, the program with 2 to 3 times a day (81.82%, 9/11) reported the highest number of significant effects, with a maximum duration of 12 months (55.56%, 5/9), followed by 6 months (33.33%, 3/9). A total of 8 trials mentioned the adverse reactions, but none was related to Baduanjin, and the dropout of participants (1.96%, 57/2912) was also not associated with Baduanjin. There is evidence for positive effects of Baduanjin in addressing perimenopausal mental disorders and postmenopausal osteoporosis, but more research is necessary to clarify best practices and quantify results.
本综述旨在评估基于临床试验的八段锦气功对围绝经期和绝经后症状的有效性和安全性。我们在 7 个数据库中进行了文献检索，检索时间截至 2023 年 6 月 30 日。提取了研究设计和基于围绝经期和绝经后阶段观察指标的信息。我们主要分析了有效性、安全性和方法学质量。共选择了 35 项试验，其中 17 项原始研究被认为具有良好的方法学质量。在围绝经期，八段锦主要用于治疗情绪障碍（63.64%，14/22），其中 6 项（42.86%，6/14）为抑郁，2 项（14.29%，2/14）为抑郁和焦虑，1 项（7.14%，1/14）为焦虑，5 项（35.71%，5/14）为睡眠障碍。运动方案的持续时间为 45 至 50 分钟（57.14%，8/14），每周 7 次（71.43%，10/14）。持续 3 个月（42.86%，6/14）的方案占运动方案的比例最高。在绝经后阶段，八段锦用于治疗骨质疏松症（84.62%，11/13）。从现有数据来看，每天练习 2 至 3 次（81.82%，9/11）的方案报告的效果最显著，最长持续时间为 12 个月（55.56%，5/9），其次是 6 个月（33.33%，3/9）。共有 8 项试验提到了不良反应，但均与八段锦无关，参与者的脱落率（1.96%，57/2912）也与八段锦无关。有证据表明八段锦对改善围绝经期精神障碍和绝经后骨质疏松症有积极作用，但需要进一步的研究来明确最佳实践并量化结果。
