Department of Neurology, Second People's Hospital of Qujing, Qujing, China.
Medicine (Baltimore). 2024 Nov 1;103(44):e40383. doi: 10.1097/MD.0000000000040383.
This study aims to explore the risk factors for carotid plaque (CP) and carotid common artery intima-media thickening (CCAIMT) and clarify the relationship between the risk factors with the number of CPs and the side of CCAIMT in a high-stroke-risk population in Qujing, Yunnan, China. Carotid ultrasonography was performed in 430 participants with high stroke risk, who were divided into different groups according to their ultrasound results. The risk factors and blood biochemical indices were recorded for assessment. The prevalence rates of CP and CCAIMT were 88.1% and 70.5%, respectively. Multivariate logistic regression analysis identified age and lack of physical exercise as risk factors of CP. Compared to participants without CP, participants who performed little physical exercise were prone to have one CP, while participants with risk factors for smoking, older age, and physical inactivity were more likely to have several CPs. Risk factors for CCAIMT were older age, male, and the levels of low density lipoprotein cholesterol. Risk factors for left CCAIMT included a history of hyperlipidemia and low density lipoprotein cholesterol, while male sex was the sole risk factor for right CCAIMT. Finally, male sex and advanced age were identified as risk factors for dual CCAIMT. The research reveals the risk factors for CP and CCAIMT, also clarifies the relationship between the risk factors, CP numbers, and the side of CCAIMT.
本研究旨在探讨颈动脉斑块(CP)和颈动脉总动脉内膜中层厚度(CCAIMT)的危险因素,并阐明在云南曲靖的高危人群中,这些危险因素与 CP 数量和 CCAIMT 侧别之间的关系。对 430 名具有高卒中风险的参与者进行了颈动脉超声检查,根据超声结果将他们分为不同的组。记录了危险因素和血液生化指标进行评估。CP 和 CCAIMT 的患病率分别为 88.1%和 70.5%。多变量逻辑回归分析确定年龄和缺乏体育锻炼是 CP 的危险因素。与没有 CP 的参与者相比,缺乏体育锻炼的参与者更容易出现一个 CP,而有吸烟、年龄较大和缺乏体力活动等危险因素的参与者更有可能出现多个 CP。CCAIMT 的危险因素包括年龄较大、男性和低密度脂蛋白胆固醇水平。CCAIMT 左侧的危险因素包括高血脂和低密度脂蛋白胆固醇史,而男性是右侧 CCAIMT 的唯一危险因素。最后,男性和高龄被确定为双侧 CCAIMT 的危险因素。该研究揭示了 CP 和 CCAIMT 的危险因素,并阐明了危险因素与 CP 数量和 CCAIMT 侧别之间的关系。