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一种新型的单侧双/多通道内镜下经椎间孔椎体间融合术,使用单轴脊柱内镜而非关节镜:技术说明及初步临床结果

A Novel Unilateral Bi/Multi-Portal Endoscopic Transforaminal Interbody Fusion Utilizing Uniaxial Spinal Endoscope Instead of Arthroscope: Technical Note and Preliminary Clinical Results.

作者信息

Yang Liyu, Zhou Long, Qiu Min, Liang Feng, Yang Liqing, Fu Qin, Ba Gen

机构信息

Department of Orthopedic, Shengjing Hospital of China Medical University, Shenyang, People's Republic of China.

出版信息

Orthop Surg. 2025 Jan;17(1):192-201. doi: 10.1111/os.14286. Epub 2024 Nov 4.

DOI:10.1111/os.14286
PMID:39497265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11735369/
Abstract

BACKGROUND

Currently, traditional UBE surgery, which is based on arthroscope, has been increasingly employed for complex lumbar degenerative diseases. However, this approach is associated with complications such as intraoperative dural sac tears, nerve root injuries, and postoperative epidural hematomas. In response to these challenges, we propose a novel technique utilizing uniaxial spinal endoscope to replace arthroscope-Unilateral Bi/Multi-Portal Endoscopy (UME). This new method has successfully treated complex lumbar disc herniation and spinal stenosis, resulting in improved postoperative outcomes and a reduction in complications. Based on the previous findings, we utilized uniaxial spinal endoscopy as the primary operating method, with the assistance of multi-portal endoscopic techniques (UME-TLIF), to perform transforaminal lumbar interbody fusion. The feasibility and preliminary clinical results have been presented in this paper.

METHODS

A total of 18 patients (8 men and 10 women, aged 52.6 ± 15.29 years) diagnosed with lumbar degenerative diseases, such as giant lumbar disc herniation, severe lumbar spinal stenosis, or lumbar spondylolisthesis, were included in this study from January 2022 to March 2023. Various parameters including operation time, ambulatory time, intraoperative fluoroscopy times, hospitalization days, and complications were recorded during the perioperative period. Clinically relevant symptoms were evaluated and documented 1, 3, 6, and 12 months postoperatively. Visual analogue scale (VAS) scores for lower back pain and leg pain, as well as the Oswestry disability index (ODI), were measured. The extent of lumbar interbody fusion was assessed using lumbar X-ray and CT scans at the 12-months follow-up. MRI was performed to assess the degree of nerve decompression in patients at the same time points. The paired t-test or Wilcoxon signed-rank test were used as statistical methods.

RESULTS

The single-segment UME-TLIF procedure had an average operation time of 211 ± 53.3 min, and the average number of X-rays taken during the operation was 11.78 ± 5.32. Patients were able to walk and perform functional exercises approximately 35.11 ± 8.41 h post-surgery, and the average duration of hospital stay was 8.5 ± 2.27 days. The VAS and ODI values at each time point post-surgery were significantly lower than the respective pre-surgery values (p < 0.05). Two patients developed postoperative sensory disturbances which significantly improved with conservative treatment. Furthermore, a follow-up CT scan conducted 12 months post-surgery showed 100% fusion rate of the surgical segments in all patients.

CONCLUSION

UME-TLIF is an endoscopy-assisted fusion procedure that minimizes muscle damage in patients and allows early rehabilitation. This technique broadens the surgical applications of uniaxial spinal endoscope as a surgical tool, particularly benefitingpatients diagnosed with severe lumbar disc herniation and lumbar instability.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/813466461604/OS-17-192-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/50b4e1a053d8/OS-17-192-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/a10eb3ba2e22/OS-17-192-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/813466461604/OS-17-192-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/50b4e1a053d8/OS-17-192-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/a10eb3ba2e22/OS-17-192-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7666/11735369/813466461604/OS-17-192-g004.jpg
摘要

背景

目前,基于关节镜的传统UBE手术已越来越多地用于治疗复杂的腰椎退行性疾病。然而,这种方法存在一些并发症,如术中硬脊膜囊撕裂、神经根损伤和术后硬膜外血肿。针对这些挑战,我们提出了一种利用单轴脊柱内窥镜替代关节镜的新技术——单侧双/多通道内窥镜检查术(UME)。这种新方法已成功治疗了复杂的腰椎间盘突出症和腰椎管狭窄症,改善了术后效果并减少了并发症。基于先前的研究结果,我们采用单轴脊柱内窥镜作为主要手术方法,并借助多通道内窥镜技术(UME-TLIF)进行经椎间孔腰椎椎间融合术。本文介绍了该手术的可行性及初步临床结果。

方法

本研究纳入了2022年1月至2023年3月期间诊断为腰椎退行性疾病(如巨大腰椎间盘突出症、严重腰椎管狭窄症或腰椎滑脱症)的18例患者(8例男性,10例女性,年龄52.6±15.29岁)。围手术期记录了包括手术时间、下床活动时间、术中透视次数、住院天数及并发症等各项参数。术后1、3、6和12个月对临床相关症状进行评估并记录。测量了下腰痛和腿痛的视觉模拟量表(VAS)评分以及Oswestry功能障碍指数(ODI)。术后12个月通过腰椎X线和CT扫描评估腰椎椎间融合的程度。同时,在相同时间点对患者进行MRI检查以评估神经减压程度。采用配对t检验或Wilcoxon符号秩检验作为统计方法。

结果

单节段UME-TLIF手术的平均手术时间为211±53.3分钟,术中平均透视次数为11.78±5.32次。患者术后约35.11±8.41小时即可行走并进行功能锻炼,平均住院天数为8.5±2.27天。术后各时间点的VAS和ODI值均显著低于术前相应值(p<0.05)。2例患者出现术后感觉障碍,经保守治疗后明显改善。此外,术后12个月的随访CT扫描显示所有患者手术节段的融合率均为100%。

结论

UME-TLIF是一种内窥镜辅助融合手术,可最大程度减少患者肌肉损伤并实现早期康复。该技术拓宽了单轴脊柱内窥镜作为手术工具的应用范围,尤其对诊断为严重腰椎间盘突出症和腰椎不稳的患者有益。

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Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus conventional interbody fusion for the treatment of degenerative lumbar spine disease: a systematic review and meta-analysis.单侧双通道内镜下经椎间孔腰椎体间融合术与传统椎间融合术治疗退变性腰椎疾病的系统评价和荟萃分析。
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