Comparison and chemometrics analysis of phenolic compounds and mineral elements in Artemisia Argyi Folium from different geographical origins.

The quality of Artemisia Argyi Folium (AAF), a traditional Chinese food ingredient, is intrinsically linked to its geographical origin, which this study explores through phenolic compounds and mineral elements. The contents of 17 phenols and 18 minerals differed significantly between geographically distinct samples according to UHPLC and ICP-MS, respectively. Chemometrics indicated that a supervised model, orthogonal partial least squares discriminant analysis (OPLS-DA), outperformed unsupervised methods at classifying AAF samples by their origins. Phenols were more effective at distinguishing samples from seven provinces, while minerals were adept at differentiating samples from the Dabie Mountain region (three provinces) and those from four other provinces. Six phenols and 10 minerals were important variables for discrimination. Complex correlations were observed between the contents of various phenols and minerals in AAF, with minerals possibly affecting the accumulation of phenols. This study provides an approach for distinguishing geographically distinct AAF samples and determining their geographical origins.