Springer Franziska, Matsuoka Ayumu, Obama Kyoko, Mehnert-Theuerkauf Anja, Uchitomi Yosuke, Fujimori Maiko
Department of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Leipzig, Germany.
Division of Supportive Care, Survivorship, and Translational Research, National Cancer Center, Institute for Cancer Control, Tokyo, Japan.
Front Psychol. 2024 Oct 22;15:1455825. doi: 10.3389/fpsyg.2024.1455825. eCollection 2024.
Older patients with cancer already represent the largest proportion of cancer survivors which will further increase in the upcoming years. However, older patients are highly underrepresented in clinical research, leading to a detrimental knowledge gap. Research on important aspects of quality of life (QoL) and associated factors for older patients with cancer is insufficient to date.
The objective of this scoping review therefore is to investigate the dimensions of QoL including functional health, life-relevant values and preferences in older adults with cancer across all tumor entities and health care settings. It will further identify medical, sociodemographic, psychosocial and geriatric aspects associated with QoL in the elderly and compare these with younger cancer patients and older non-cancer cases.
Published articles investigating QoL dimensions and associated factors in older patients with cancer, i.e., exclusively patients ≥65 years or mean/median age ≥ 70 years for age-mixed samples, or that compare results of older with younger cancer patients or with older non-cancer cases will be considered for this scoping review. Older patients with cancer across all tumor entities, disease stages and health care setting will be included. PubMed and PsychINFO databases will be searched for relevant articles. Abstracts and titles will be screened for basic inclusion, and two independent reviewers will conduct a full text screening to evaluate the age criteria and decide on the final inclusion of the study. Data on study and participant characteristics, QoL dimensions and geriatric factors will be extracted using a data extraction sheet. Results will be summarized descriptively to address the objectives of this review.
The findings of this scoping review will provide valuable insights into central dimensions of QoL, including values, preferences and functional health in older adults with cancer, and help to improve targeted interventions and healthcare planning.
老年癌症患者已经是癌症幸存者中的最大群体，且在未来几年这一比例还会进一步增加。然而，老年患者在临床研究中的代表性严重不足，导致了有害的知识缺口。迄今为止，关于老年癌症患者生活质量（QoL）的重要方面及其相关因素的研究尚不充分。
因此，本范围综述的目的是调查所有肿瘤类型和医疗环境下老年癌症患者的生活质量维度，包括功能健康、与生活相关的价值观和偏好。它还将识别与老年人生活质量相关的医学、社会人口统计学、心理社会和老年医学方面，并将这些与年轻癌症患者和老年非癌症患者进行比较。
本范围综述将纳入已发表的研究老年癌症患者生活质量维度及其相关因素的文章，即仅研究年龄≥65岁的患者或年龄混合样本中平均/中位年龄≥70岁的患者，或者比较老年与年轻癌症患者或老年非癌症患者结果的文章。将纳入所有肿瘤类型、疾病阶段和医疗环境下的老年癌症患者。将在PubMed和PsychINFO数据库中搜索相关文章。将筛选摘要和标题以确定基本纳入标准，两名独立评审员将进行全文筛选，以评估年龄标准并决定最终纳入的研究。将使用数据提取表提取关于研究和参与者特征、生活质量维度和老年医学因素的数据。将对结果进行描述性总结，以实现本综述的目标。
本范围综述的结果将为癌症老年患者生活质量的核心维度提供有价值的见解，包括价值观、偏好和功能健康，并有助于改进针对性干预措施和医疗规划。
