Kajiwara Yoshiki, Ueno Hideki
Department of Surgery National Defense Medical College Tokorozawa Japan.
Ann Gastroenterol Surg. 2024 Aug 19;8(6):977-986. doi: 10.1002/ags3.12853. eCollection 2024 Nov.
Pivotal articles that had been published between 2022 and 2023 on surgical and perioperative adjuvant treatments for locally advanced colorectal cancer (CRC) were reviewed. This review focuses on new evidence in the following areas: optimization of surgical procedures for colon cancer, including the optimal length of bowel resection and use of the no-touch isolation technique; minimally invasive surgery for rectal cancer, such as laparoscopic transanal total mesorectal excision and robotic surgery; neoadjuvant treatments for rectal cancer, including total neoadjuvant therapy; neoadjuvant chemotherapy for colon cancer; and postoperative adjuvant chemotherapy for Stage II and III colon cancer. Although the current understanding may not enable perfect decision-making for patients and medical professionals, ongoing advancements are expected to result in more effective personalized treatment plans, ultimately improving the prognosis and quality of life of patients.
回顾了2022年至2023年间发表的关于局部晚期结直肠癌（CRC）手术及围手术期辅助治疗的关键文章。本综述聚焦于以下领域的新证据：结肠癌手术程序的优化，包括肠切除的最佳长度及非接触隔离技术的应用；直肠癌的微创手术，如腹腔镜经肛门全直肠系膜切除术和机器人手术；直肠癌的新辅助治疗，包括全新辅助治疗；结肠癌的新辅助化疗；以及II期和III期结肠癌的术后辅助化疗。尽管目前的认知可能无法让患者和医疗专业人员做出完美决策，但预计持续的进展将带来更有效的个性化治疗方案，最终改善患者的预后和生活质量。
