Imaoka Yuki, Ohira Masahiro, Akabane Miho, Sasaki Kazunari, Ohdan Hideki
Department of Gastroenterological and Transplant Surgery Graduate School of Biomedical and Health Sciences Hiroshima University, Hiroshima University Hiroshima Japan.
Division of Abdominal Transplant Stanford University School of Medicine Stanford California USA.
Ann Gastroenterol Surg. 2024 Jun 4;8(6):987-998. doi: 10.1002/ags3.12816. eCollection 2024 Nov.
This review discusses the increasing global trend towards an aging population, which has resulted in a growing number of surgeries being performed on elderly patients, particularly those living with cancer. The focus was on the implications of abdominal aortic calcification (AAC), an indicator of systemic atherosclerosis, in these patients. This comprehensive review provided evidence detailing the complex processes of atherosclerosis and vascular calcification and various approaches to assess this condition. The prevalence of AAC is related to multiple factors, including cardiovascular disease, inflammation, frailty in various types of gastroenterological surgery. Additionally, notable links were found between AAC, postoperative complications, and patient survival following gastroenterological surgery. This study highlights how AAC could negatively impact the health status of elderly patients and undermine treatment efficacy, stressing the need for more research in this domain to improve patient outcomes.
本综述讨论了全球人口老龄化趋势的加剧,这导致老年患者,尤其是癌症患者接受手术的数量不断增加。重点关注腹主动脉钙化(AAC)这一全身性动脉粥样硬化指标在这些患者中的影响。这篇全面的综述提供了详细阐述动脉粥样硬化和血管钙化复杂过程以及评估这种状况的各种方法的证据。AAC的患病率与多种因素相关,包括心血管疾病、炎症、各类胃肠外科手术中的虚弱状态。此外,在AAC、术后并发症以及胃肠外科手术后患者生存之间发现了显著联系。本研究强调了AAC如何可能对老年患者的健康状况产生负面影响并削弱治疗效果,强调在这一领域需要更多研究以改善患者预后。