Kim Da-Hye, Yang Hyeon Mo, Song Ju-Yong, Park Jina, Kwon Byung-Yeon, Vu Anh Viet, Lee Dae Sung, Lee Kyung-Woo
Department of Animal Science and Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Republic of Korea.
Medi Bio Lab Co., Ltd., Seoul Republic of Korea.
Poult Sci. 2024 Dec;103(12):104477. doi: 10.1016/j.psj.2024.104477. Epub 2024 Oct 31.
The objective of this study was to evaluate the effects of dietary mangosteen peel preparations, either powdered (MspP) or ethanolic extract (MspE), on the growth performance, meat quality, immune response, gut health, serum biochemical profiles, and antioxidant activity of broiler chicks. A total of 480 day-old straight-run broiler chicks (Ross 308) were randomly placed into four treatments, with eight replicates of 12 chicks each, and subjected to one of the four experimental diets for 21 days. The corn and soybean meal-based diet was supplemented with 2% MspP (20 g per kg of diet) or 0.05% and 0.1% MspE (0.5 g and 1.0 g per kg of diet). Data were analyzed using analysis of variance, and post hoc comparisons of treatments were performed using Tukey's Honestly Significant Difference test. From days 0 to 21, dietary mangosteen peel preparations did not affect growth performance (body weight gain, feed intake, and feed conversion ratio), thigh meat and tibia characteristics, serum markers of innate immunity (interferon-r, interleukin-10, alpha-1-acid glycoprotein, and nitric oxide), and ileal morphology in broiler chicks (P > 0.05). Dietary mangosteen peel preparations increased the percentage of high-density lipoprotein cholesterol and decreased the relative concentrations of isobutyrate and branched-chain fatty acids in the cecal digesta compared with the control chickens. Notably, dietary mangosteen peel preparations altered the antioxidant characteristics of the serum, liver, and thigh meat. Dietary MspE increased glutathione peroxidase (P = 0.039) in the serum and catalase in the serum (P = 0.008), liver (P = 0.05), and thigh meat (P = 0.01) compared to the control group. In addition, dietary MspP increased catalase levels in thigh meat compared to those in the control diet-fed chickens (P = 0.01). The concentration of malondialdehyde, an indicator of lipid peroxidation, was lower in all chicks-fed diets containing mangosteen peel preparations; however, statistical significance was only noted in the serum samples (P < 0.0001). Collectively, our study shows that dietary mangosteen peel preparations are potent natural antioxidants that can be used as functional dietary additives to effectively mitigate oxidative stress in broiler chicks.
本研究的目的是评估食用山竹果皮制剂（粉末状，即MspP；或乙醇提取物，即MspE）对肉鸡生长性能、肉质、免疫反应、肠道健康、血清生化指标和抗氧化活性的影响。总共480只一日龄的罗斯308品系直选肉鸡被随机分为四个处理组，每组8个重复，每个重复12只鸡，并在21天内分别饲喂四种实验日粮之一。以玉米和豆粕为基础的日粮分别添加了2%的MspP（每千克日粮20克）或0.05%和0.1%的MspE（每千克日粮0.5克和1.0克）。数据采用方差分析进行分析，处理组之间的事后比较采用Tukey氏真实显著差异检验。在第0至21天期间，食用山竹果皮制剂对肉鸡的生长性能（体重增加、采食量和饲料转化率）、大腿肉和胫骨特性、先天性免疫血清标志物（干扰素-γ、白细胞介素-10、α-1-酸性糖蛋白和一氧化氮）以及回肠形态均无影响（P>0.05）。与对照鸡相比，食用山竹果皮制剂提高了高密度脂蛋白胆固醇的百分比，并降低了盲肠内容物中异丁酸和支链脂肪酸的相对浓度。值得注意的是，食用山竹果皮制剂改变了血清、肝脏和大腿肉的抗氧化特性。与对照组相比，日粮添加MspE可提高血清中的谷胱甘肽过氧化物酶水平（P = 0.039）以及血清、肝脏（P = 0.05）和大腿肉中的过氧化氢酶水平（P = 0.01）。此外与饲喂对照日粮的鸡相比，日粮添加MspP可提高大腿肉中的过氧化氢酶水平（P = 0.01）。在所有饲喂含山竹果皮制剂日粮的雏鸡中，脂质过氧化指标丙二醛的浓度均较低；然而，仅在血清样本中具有统计学意义（P<0.0001）。总体而言，我们的研究表明，食用山竹果皮制剂是有效的天然抗氧化剂，可作为功能性饲料添加剂来有效减轻肉鸡的氧化应激。
