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包含阶梯式随机临床试验的网站:促进高质量的试验和方法学研究。

A website for cluster randomised trials including stepped wedge: facilitating quality trials and methodological research.

机构信息

Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, Yvonne Carter Building, 58 Turner Street, London, E1 2AB, UK.

Department of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

出版信息

Trials. 2024 Nov 6;25(1):742. doi: 10.1186/s13063-024-08597-6.

Abstract

BACKGROUND

A cluster randomised trial is a randomised controlled trial in which groups of individuals (clusters) are randomised to treatment arms. Stepped wedge cluster randomised trials are a type of cluster randomised trial where clusters are randomised to sequences. These trial designs are important for impacting decision-making, and it is therefore important that they be well-conducted and reported.

MAIN BODY

In November 2018, we created a new website dedicated to cluster randomised trials, including stepped wedge designs: https://clusterrandomisedtrials.qmul.ac.uk/ . The idea for the website emerged from the conference on Current Developments in Cluster Randomised Trials and Stepped Wedge Designs held in November 2016 at Queen Mary University of London, with the aim to provide an online resource to facilitate quality trials and methodological research on these types of trial. The website is divided into sections covering Design, Analysis and Reporting for traditional (i.e. parallel two-arm) cluster randomised trials and stepped wedge designs and contains resources in the form of hyperlinks to relevant papers along with brief explanations. A noticeboard page provides details on announcements, events, and past events.

CONCLUSION

We aim to keep the site updated with the latest publications and events related to cluster randomised trials, and welcome suggestions from the research community on further resources or events to add. We hope that the site will facilitate high-quality traditional and stepped wedge cluster randomised trials.

摘要

背景

整群随机对照试验是一种将个体(整群)随机分配到治疗组的随机对照试验。阶梯式楔形整群随机试验是一种整群随机试验,其中整群被随机分配到不同的序列中。这些试验设计对于影响决策非常重要,因此,良好的设计和报告非常重要。

主要内容

2018 年 11 月,我们创建了一个专门用于整群随机试验(包括阶梯式楔形设计)的新网站:https://clusterrandomisedtrials.qmul.ac.uk/。该网站的创意源于 2016 年 11 月在伦敦玛丽女王大学举行的“当前整群随机试验和阶梯式楔形设计发展”会议,旨在提供一个在线资源,以促进这些类型试验的高质量试验和方法学研究。该网站分为涵盖传统(即平行双臂)整群随机试验和阶梯式楔形设计的设计、分析和报告部分,包含以超链接形式呈现的相关论文资源以及简要说明。一个公告板页面提供了有关公告、活动和过去活动的详细信息。

结论

我们的目标是保持网站的最新更新,包括与整群随机试验相关的最新出版物和活动,并欢迎研究界就进一步的资源或活动提出建议。我们希望该网站将促进高质量的传统和阶梯式楔形整群随机试验。

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