Husain A N, Leestma J E
J Neurosurg. 1986 Apr;64(4):657-61. doi: 10.3171/jns.1986.64.4.0657.
Astroblastoma is a rare glial tumor occurring predominantly in the cerebral hemispheres of young adults. Foci of astroblastoma-like patterns are commonly found in glioblastomas and other malignant glial tumors and cause confusion over the classification of the tumor as an individual entity. However, the existence of astroblastoma in histologically pure form and its typically long history, as compared with the more aggressive gliomas in which it may occur as a pattern, distinguish it as a separate and distinct tumor. A case of pure astroblastoma of the cerebral hemisphere is reported in a 3-year-old child with a 5-year course. The tumor has been resected five times, and its pattern has remained the same in all recurrences. The child is presently alive with some neurological deficit. The immunohistochemical and electron microscopical findings of this tumor are presented, and the historical development of the entity is discussed.
成星形细胞瘤是一种罕见的神经胶质肿瘤，主要发生于年轻成年人的大脑半球。成星形细胞瘤样形态的病灶常见于胶质母细胞瘤和其他恶性神经胶质肿瘤中，这使得将该肿瘤作为一个独立实体进行分类时产生混淆。然而，组织学上纯粹形式的成星形细胞瘤的存在及其通常较长的病程，与它可能作为一种形态出现的更具侵袭性的胶质瘤相比，使其成为一种单独且独特的肿瘤。本文报道了一名3岁儿童患大脑半球纯化成星形细胞瘤且病程长达5年的病例。该肿瘤已进行了5次切除，每次复发时其形态均保持不变。该患儿目前仍存活，但存在一些神经功能缺损。本文展示了该肿瘤的免疫组化和电子显微镜检查结果，并讨论了该实体的历史发展。
