经皮氧合监测：正常范围是多少？

Transcutaneous monitoring of oxygenation: what is normal?

作者信息

Mok J Y, McLaughlin F J, Pintar M, Hak H, Amaro-Galvez R, Levison H

出版信息

J Pediatr. 1986 Mar;108(3):365-71. doi: 10.1016/s0022-3476(86)80874-5.

Abstract

We examined 55 infants on 119 occasions, from birth to 6 months, to obtain normal data and to establish guidelines for the management of oxygen-dependent infants with chronic lung disease. Transcutaneous oxygen tension (tcPo2) and saturation (tcSao2) were monitored during four states: awake, feeding, quiet sleep, and active sleep. Lowest values (mean +/- SD) for tcSao2 were recorded in all states during the first week of life: awake 96.2% +/- 2.6%, feeding 91.2% +/- 3.7%, quiet sleep 93.2% +/- 2.9%, and active sleep 92.1% +/- 2.9%. After the first week the results were affected by state rather than age, with differences observed between awake and feeding (P less than 0.0001), awake and asleep (P less than 0.00001), and quiet sleep and active sleep (P less than 0.001). The findings for tcPo2 were less consistent and probably affected by the characteristics of skin. In the first week, values were as follows: awake 83.5 +/- 10.1 mm Hg, feeding 73.4 +/- 10.1 mm Hg, quiet sleep 78.5 +/- 10.9 mm Hg, and active sleep 73.4 +/- 11.4 mm Hg. Subsequently, only the state effect remained, and significant differences existed between awake and feeding (P less than 0.0001) and awake and asleep (P less than 0.00001). We conclude that transcutaneous blood gas measurements are affected by state of the infant.

摘要

我们对55名婴儿进行了119次检查，从出生至6个月大，以获取正常数据并制定对患有慢性肺病的氧依赖型婴儿的管理指南。在清醒、进食、安静睡眠和活跃睡眠四种状态下监测经皮氧分压（tcPo2）和饱和度（tcSao2）。在出生后第一周，所有状态下tcSao2的最低值（均值±标准差）如下：清醒时96.2%±2.6%，进食时91.2%±3.7%，安静睡眠时93.2%±2.9%，活跃睡眠时92.1%±2.9%。第一周后，结果受状态而非年龄影响，清醒与进食之间（P<0.0001）、清醒与睡眠之间（P<0. 00001）以及安静睡眠与活跃睡眠之间（P<0.001）均观察到差异。tcPo2的结果不太一致，可能受皮肤特性影响。在第一周，其值如下：清醒时83.5±10.1毫米汞柱，进食时73.4±10.1毫米汞柱，安静睡眠时78.5±10.9毫米汞柱，活跃睡眠时73.4±11.4毫米汞柱。随后，仅存在状态效应，清醒与进食之间（P<0.0001）以及清醒与睡眠之间（P<0.00001）存在显著差异。我们得出结论，经皮血气测量受婴儿状态影响。