Trompeter Nora, Dârvariu Ștefana, Brieva-Toloza Anna V, Opitz Marie-Christine, Rabelo-da-Ponte Francisco Diego, Sharpe Helen, Desrivieres Sylvane, Schmidt Ulrike, Micali Nadia
Great Ormond Street Institute of Child Health, UCL, 30 Guilford Street, London, WC1N 1EH, UK.
Center for Eating and Feeding Disorders Research, Mental Health Center Ballerup, Copenhagen University Hospital, Mental Health Services CPH, Copenhagen, Denmark.
Eur Child Adolesc Psychiatry. 2024 Nov 7. doi: 10.1007/s00787-024-02601-9.
Anxiety symptoms and eating disorder symptoms commonly co-occur in adolescents. However, there is divergent evidence on the prospective relationship between the two factors. This systematic review and meta-analysis summarises the existing literature on the prospective and bi-directional relationship between anxiety symptoms and eating disorder symptoms in adolescence. A systematic search across six databases was conducted on the 11th June 2024. Studies were included if they assessed the prospective relationship between anxiety symptoms and eating disorder symptoms, or vice versa, in adolescence. 19,591 studies were screened, of which 54 studies met inclusion criteria and were included in the full review. Four meta-analyses were conducted. Anxiety symptoms were associated with subsequent eating disorder symptoms, increases in eating disorder symptoms, and higher odds of eating disorders, including their onset. Conversely, eating disorder symptoms were associated with subsequent anxiety symptoms, increases in anxiety symptoms, and higher odds of subsequent anxiety disorders. Current evidence suggests that anxiety symptoms and eating disorder symptoms do not merely co-occur during adolescence, but are prospectively and bi-directionally linked. Further research is needed to understand the underlying mechanisms of this relationship, as well as individual differences in symptom trajectories.
焦虑症状和饮食失调症状在青少年中通常同时出现。然而，关于这两个因素之间的前瞻性关系，证据并不一致。本系统综述和荟萃分析总结了关于青少年焦虑症状和饮食失调症状之间前瞻性和双向关系的现有文献。2024年6月11日对六个数据库进行了系统检索。如果研究评估了青少年焦虑症状和饮食失调症状之间的前瞻性关系，反之亦然，则纳入该研究。共筛选了19591项研究，其中54项研究符合纳入标准并纳入全面综述。进行了四项荟萃分析。焦虑症状与随后的饮食失调症状、饮食失调症状的增加以及饮食失调（包括其发病）的较高几率相关。相反，饮食失调症状与随后的焦虑症状、焦虑症状的增加以及随后患焦虑症的较高几率相关。目前的证据表明，焦虑症状和饮食失调症状不仅在青少年时期同时出现，而且在前瞻性和双向性上存在联系。需要进一步研究以了解这种关系的潜在机制，以及症状轨迹的个体差异。
