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牙龈良性纤维组织细胞瘤:1例罕见病例报告

Benign Fibrous Histiocytoma of Gingiva: A Rare Case Report.

作者信息

Sangala Bhavani Nagendra, Jawdekar Ashwin, Choudhari Sheetal S, Tank Urvashi R, Buva Kirti Balkrishna, Deshpande Sneha Masne

机构信息

Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.

Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India.

出版信息

Contemp Clin Dent. 2024 Jul-Sep;15(3):202-205. doi: 10.4103/ccd.ccd_535_23. Epub 2024 Sep 25.

DOI:10.4103/ccd.ccd_535_23
PMID:39512292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11540204/
Abstract

Fibrous histiocytoma is a benign soft-tissue neoplasm that commonly involves the dermis. It is rare in the oral cavity. This lesion creates a diagnostic dilemma due to its nonspecific clinical appearance and microscopic similarities with other benign fibrous tissue lesions. Microscopically, it shows the proliferation of both spindle-shaped fibroblasts and histiocytes. Surgical excision is the treatment of choice with a good prognosis. The purpose of this paper is to report a rare case of gingival benign fibrous histiocytoma occurring in an 11-year-old female patient. The diagnosis of this lesion is based on combined clinical, histopathological, and immunohistochemical features.

摘要

纤维组织细胞瘤是一种常见累及真皮的良性软组织肿瘤。它在口腔中较为罕见。由于其非特异性的临床表现以及在显微镜下与其他良性纤维组织病变相似,该病变造成了诊断上的难题。在显微镜下,它表现为梭形成纤维细胞和组织细胞的增殖。手术切除是首选治疗方法,预后良好。本文旨在报告一例发生于一名11岁女性患者的罕见牙龈良性纤维组织细胞瘤病例。该病变的诊断基于临床、组织病理学和免疫组化特征的综合判断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/e327a5c32fa5/CCD-15-202-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/fda7de820ced/CCD-15-202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/05cf92df7580/CCD-15-202-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/3870bdbb0ac0/CCD-15-202-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/e327a5c32fa5/CCD-15-202-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/fda7de820ced/CCD-15-202-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/05cf92df7580/CCD-15-202-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/3870bdbb0ac0/CCD-15-202-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6343/11540204/e327a5c32fa5/CCD-15-202-g004.jpg

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本文引用的文献

1
Benign fibrous histiocytoma of the oral and maxillofacial region: A systematic review.口腔颌面部良性纤维组织细胞瘤:系统评价。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Feb;133(2):e43-e56. doi: 10.1016/j.oooo.2021.07.003. Epub 2021 Jul 15.
2
Benign fibrous histiocytoma of the lower lip.下唇良性纤维组织细胞瘤
J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S97-S100. doi: 10.4103/jomfp.JOMFP_351_19. Epub 2020 Feb 28.
3
Benign Fibrous Histiocytomas of the Oral Mucosa: Report on Three Cases and Review of the Literature.
口腔黏膜良性纤维组织细胞瘤:三例报告并文献复习
Dermatopathology (Basel). 2015 Apr 29;2(2):52-60. doi: 10.1159/000381618. eCollection 2015 Apr-Jun.
4
Benign fibrous histiocytoma of the tongue.舌部良性纤维组织细胞瘤
Indian J Dent Res. 2013 Sep-Oct;24(5):635-8. doi: 10.4103/0970-9290.123419.
5
Benign fibroushistiocytoma of the gingiva.牙龈良性纤维组织细胞瘤
J Pharm Bioallied Sci. 2013 Jul;5(Suppl 2):S166-8. doi: 10.4103/0975-7406.114324.
6
Benign fibrous histiocytoma of the buccal mucosa: case report and literature review.颊黏膜良性纤维组织细胞瘤:病例报告及文献复习
Case Rep Med. 2010;2010:306148. doi: 10.1155/2010/306148. Epub 2010 Jun 17.