Egelund Eric F, Jula Alana, Rish Kathleen, Casapao Anthony M
Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Jacksonville, Florida, USA.
Infectious Disease Pharmacokinetics Laboratory, Gainesville, Florida, USA.
J Vet Pharmacol Ther. 2025 Jan;48(1):1-14. doi: 10.1111/jvp.13492. Epub 2024 Nov 12.
Sea turtles face various threats to survival, primarily due to human activities, such as bycatch, vessel strikes, pollution, and climate change. Many of these activities can lead to illness or injuries, increasing the risk of infection. Treating infections appropriately and effectively requires knowledge of antimicrobial properties and their ability to eradicate microbes without harm to the sea turtle. Robust pharmacokinetic studies, therefore, are important for appropriate dosing. Herein, we review the studies detailing the pharmacokinetic properties of antimicrobials in sea turtles conducted to date.
海龟面临着各种生存威胁，主要是由于人类活动，如兼捕、船只撞击、污染和气候变化。这些活动中的许多都可能导致疾病或受伤，增加感染风险。适当且有效地治疗感染需要了解抗菌特性及其在不伤害海龟的情况下根除微生物的能力。因此，强大的药代动力学研究对于适当给药很重要。在此，我们回顾了迄今为止所进行的详细阐述海龟体内抗菌药物药代动力学特性的研究。
