在一项人体感染对照模型的唾液样本中未检测到诺如病毒。
Lack of Detection of Norwalk Virus in Saliva Samples From a Controlled Human Infection Model.
作者信息
Atmar Robert L, Neill Frederick H, Hayes Nicole M, Opekun Antone R, Graham David Y, Estes Mary K, Ramani Sasirekha
机构信息
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
出版信息
Open Forum Infect Dis. 2024 Nov 4;11(11):ofae652. doi: 10.1093/ofid/ofae652. eCollection 2024 Nov.
Following recent reports of norovirus replication in salivary gland cells, we examined whether the prototype norovirus strain, Norwalk virus (GI.1), could be detected in the saliva of 21 experimentally infected persons. Viral RNA was not detected in saliva 2 and 7 days after challenge despite high levels being present in feces.
继最近有关于诺如病毒在唾液腺细胞中复制的报道之后，我们检测了21名实验性感染者的唾液中是否能检测到诺如病毒原型株——诺沃克病毒（GI.1）。尽管在粪便中检测到了高水平的病毒，但在攻击后第2天和第7天的唾液中未检测到病毒RNA。
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