细菌小 RNA 对肠道定植产生重大影响。
Bacterial small RNA makes a big impact for gut colonization.
机构信息
Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg; Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.
出版信息
Cell Host Microbe. 2024 Nov 13;32(11):1875-1877. doi: 10.1016/j.chom.2024.10.010.
The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (SrcF), a sRNA from a prevalent gut bacterium Segatella copri. SrcF promotes colonization of S. copri by regulating bacterial degradation of complex dietary carbohydrates.
非编码小 RNA（sRNAs）在人类微生物组中的功能在很大程度上仍未被探索。在本期《细胞宿主与微生物》中，El Mouali 等人鉴定了一种来自常见肠道细菌 Segatella copri 的 sRNA，即 Segatella RNA 定植因子（SrcF）。SrcF 通过调节细菌对复杂膳食碳水化合物的降解来促进 S. copri 的定植。
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