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饮食失调中精神病的早期检测:是不必要的还是有益的补充?

Early Detection of Psychosis in Eating Disorders: Unnecessary or a Useful Addition?

作者信息

de Bont Paul A J M, Seelen-de Lang Birgit, Maas Joyce, Bodde Nynke M G

机构信息

Mental Health Organization 'GGZ Oost Brabant', Early Detection and Intervention (EDI) Team, Boekel, The Netherlands.

Mental Health Organization 'GGZ Oost Brabant', Centre for Eating Disorders, Helmond, The Netherlands.

出版信息

Early Interv Psychiatry. 2025 Jan;19(1):e13630. doi: 10.1111/eip.13630. Epub 2024 Nov 14.

Abstract

AIM

The absence of consensus regarding the presence and interpretation of certain symptoms as indicative of either a psychosis spectrum disorder or an eating disorder (ED) can hinder cooperation amongst treatment programmes for the early detection of psychosis and an ED. This study trans-diagnostically assessed the prevalence and co-occurrence of at-risk mental states for a psychosis (ARMS) or the risk of having an ED (EDr), and it explored the characteristics of ARMS profiles of individuals with an EDr.

METHOD

This cross-sectional and observational-prevalence study used assessment outcomes from an ED screening instrument (SCOFF), a psychosis prodromal screening questionnaire (PQ16) and a CAARMS interview (to evaluate the possibility of ARMS) with newly admitted outpatients aged 16-35 who were referred for various kinds of non-psychotic disorders from a secondary Mental Health Care Centre in the Netherlands. Data analysis consisted of calculating prevalences, associations amongst variables and conditional probabilities.

RESULTS

Of the 736 individuals who were screened, an EDr was identified in 51.2% and 49.0% of the participants who scored high on the PQ16, half of whom also completed the CAARMS interview. The results indicated that 53.0% of the participants were classified as not having ARMS, 28.3% as having ARMS and 18.7% as having a psychosis. EDr patients presented with symptoms of a psychotic spectrum disorder, which included both ED-consistent and ED-inconsistent symptoms. There were relatively frequent endorsements of the two subscale items guilt/punishment and ideas of reference.

CONCLUSIONS

From a trans-diagnostical perspective, the results indicate that collaboration amongst ED programmes and psychosis prevention interventions should be strongly encouraged. Future researchers are encouraged to conduct studies that assess associations amongst and features of psychotic spectrum symptoms in EDs. The unexpectedly high proportion of EDr suggests that a co-morbid ED in other kinds of psychopathology is being overlooked.

摘要

目的

对于某些症状的存在及解读缺乏共识,这些症状被视为精神病性谱系障碍或进食障碍(ED)的指标,这可能会阻碍精神病和进食障碍早期检测治疗项目之间的合作。本研究从跨诊断角度评估了精神病风险精神状态(ARMS)或患进食障碍风险(EDr)的患病率及共现情况,并探讨了有EDr的个体的ARMS特征。

方法

这项横断面观察性患病率研究使用了进食障碍筛查工具(SCOFF)、精神病前驱筛查问卷(PQ16)以及CAARMS访谈(以评估ARMS的可能性)的评估结果,这些结果来自荷兰一家二级精神卫生保健中心新收治的16至35岁因各种非精神病性障碍前来就诊的门诊患者。数据分析包括计算患病率、变量之间的关联以及条件概率。

结果

在接受筛查的736名个体中,PQ16得分高的参与者中有51.2%和49.0%被确定有EDr,其中一半还完成了CAARMS访谈。结果表明,53.0%的参与者被归类为没有ARMS,28.3%有ARMS,18.7%有精神病。EDr患者表现出精神病性谱系障碍的症状,包括与进食障碍一致和不一致的症状。内疚/惩罚和牵连观念这两个分量表项目的认可相对频繁。

结论

从跨诊断角度来看,结果表明应大力鼓励进食障碍项目与精神病预防干预措施之间的合作。鼓励未来的研究人员开展研究,评估进食障碍中精神病性谱系症状之间的关联及特征。EDr出乎意料的高比例表明,其他类型精神病理学中共病的进食障碍被忽视了。

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