Dental Health Department, College of Applied Medical Sciences, King Saud University, 11451 Riyadh, Saudi Arabia.
Pediatric Dentistry and Orthodontics Department, College of Dentistry, King Saud University, 11451 Riyadh, Saudi Arabia.
J Clin Pediatr Dent. 2024 Nov;48(6):69-77. doi: 10.22514/jocpd.2024.127. Epub 2024 Nov 3.
Fissure sealants commonly exhibit weak mechanical and physical properties, potentially compromising their effectiveness in preventing dental caries. Therefore, this laboratory study aimed to synthesize and characterize experimental pit and fissure sealants in comparison with a commercially available sealant. Three different formulations of experimental pit and fissure sealing materials were synthesized using a blend of bisphenol A-glycidyl methacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) monomers. The resin composition encompassed 70 wt.%, with 30 wt.% fillers comprising 10 wt.% silica in each composition, while 20 wt.% bioactive glasses. Specifically, group G1 employed Biomin F powder, group G2 utilized Biomin C powder, and group G3 incorporated S53P4 powder. The control group (GC) was a commercially available pit and fissure sealant (Seal-Rite). Ten disk-shaped specimens from each study group were fabricated (n = 10/group). The surface roughness, water contact angle, nanohardness (nH), elastic modulus (EM), water solubility and sorption were statistically evaluated using a one-way analysis of variance ( < 0.05). The surface roughness of the G1 & G2 groups and the water contact angle of G1, G2 & G3 groups were significantly lower compared to the control group ( < 0.05). However, nH, EM, water solubility, and sorption were notably higher in the control group compared to the experimental groups, except G1, which exhibited no significant difference from the control group ( > 0.05). The inclusion of micron-sized Biomin F powder in the experimental Bis-GMA/TEGDMA resin formulation demonstrated advantageous effects in reducing surface roughness and forming a lower contact angle without compromising the mechanical attributes.
窝沟封闭剂通常表现出较弱的机械和物理性能，这可能会降低其预防龋齿的效果。因此，本实验室研究旨在合成和表征实验性窝沟封闭剂，并与市售封闭剂进行比较。使用双酚 A-缩水甘油甲基丙烯酸酯（Bis-GMA）和三乙二醇二甲基丙烯酸酯（TEGDMA）单体的混合物合成了三种不同配方的实验性窝沟封闭材料。树脂组成包括 70wt%，填料组成 30wt%，每种组成各含 10wt%二氧化硅，同时含有 20wt%生物活性玻璃。具体而言，G1 组使用 Biomin F 粉末，G2 组使用 Biomin C 粉末，G3 组使用 S53P4 粉末。对照组（GC）是一种市售的窝沟封闭剂（Seal-Rite）。从每个研究组制备了 10 个圆盘状样本（n = 10/组）。使用单向方差分析（ < 0.05）对表面粗糙度、水接触角、纳米硬度（nH）、弹性模量（EM）、水溶性和吸湿性进行了统计学评估。与对照组相比，G1 和 G2 组的表面粗糙度和 G1、G2 和 G3 组的水接触角明显降低（ < 0.05）。然而，对照组的 nH、EM、水溶性和吸湿性明显高于实验组，除 G1 组与对照组无显著差异（ > 0.05）。在实验性 Bis-GMA/TEGDMA 树脂配方中加入微米级的 Biomin F 粉末，在不降低机械性能的情况下，有利于降低表面粗糙度和形成较低的接触角。
