Khan Aftab Ahmed, AlKhureif Abdulaziz Abdullah, Mirza Eraj Humayun, AlHassoun Raghad Khalid, Wasi Aisha, Matinlinna Jukka
Dental Biomaterials Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia.
Biomedical Engineering Department, NED University of Engineering and Technology, Karachi 69230, Pakistan.
Bioengineering (Basel). 2025 May 13;12(5):515. doi: 10.3390/bioengineering12050515.
Tissue conditioners are temporary lining materials applied to dentures to soothe and cushion inflamed or traumatized oral tissues, typically resulting from ill-fitting dentures. This laboratory study aimed to evaluate the physicomechanical properties of a clinical tissue conditioner with 0.5 and 1 wt.% of silanized, micron-sized, E-glass fibers. The experimental tissue conditioners were characterized based on their molecular structure, surface roughness, contact angle, tensile strength, dimensional stability, water sorption, and solubility. The results were analyzed by two-way ANOVA (factors: material composition and aging) and the post hoc Tukey's test. FTIR analysis revealed characteristic peaks at 1710-1720 cm, 2800-3000 cm, and 1400 cm, indicating a strong interaction between the tissue conditioner and the micron-sized glass fibers. Tensile strength was highest at baseline but declined in all groups after 14 days of aging, with the 0.5 wt.% glass fiber group showing the least reduction. Linear dimensional changes remained consistent across all groups. Surface roughness increased in all groups after 14 days, though the 0.5 wt.% glass fiber group exhibited the smallest increase. Water contact angles ranged from 71° to 92°, suggesting adequate surface wettability for clinical use. The experimental groups consistently demonstrated lower water sorption and solubility values. The 0.5 wt.% glass fiber formulation showed the potential to improve clinical performance by its reduced water sorption and solubility. However, long-term studies and clinical trials are necessary to validate the clinical effectiveness of this formulation.
组织调理剂是一种临时衬里材料，用于义齿，以舒缓和缓冲发炎或受创伤的口腔组织，这些组织通常是由不合适的义齿引起的。这项实验室研究旨在评估含有0.5重量%和1重量%硅烷化微米级E玻璃纤维的临床组织调理剂的物理机械性能。基于其分子结构、表面粗糙度、接触角、拉伸强度、尺寸稳定性、吸水性和溶解性对实验性组织调理剂进行了表征。通过双向方差分析（因素：材料组成和老化）和事后Tukey检验对结果进行了分析。傅里叶变换红外光谱分析显示在1710 - 1720厘米、2800 - 3000厘米和1400厘米处有特征峰，表明组织调理剂与微米级玻璃纤维之间有强烈的相互作用。拉伸强度在基线时最高，但在老化14天后所有组均下降，其中0.5重量%玻璃纤维组下降最少。所有组的线性尺寸变化保持一致。14天后所有组的表面粗糙度均增加，不过0.5重量%玻璃纤维组增加最小。水接触角在71°至92°之间，表明具有适合临床使用的表面润湿性。实验组的吸水性和溶解性值始终较低。0.5重量%玻璃纤维配方因其降低的吸水性和溶解性显示出改善临床性能的潜力。然而，需要长期研究和临床试验来验证该配方的临床有效性。
