Jabs D A, Miller N R, Newman S A, Johnson M A, Stevens M B
Arch Ophthalmol. 1986 Apr;104(4):564-8. doi: 10.1001/archopht.1986.01050160120026.
We report data from seven cases of optic neuropathy in systemic lupus erythematosus. The visual outcome varied, but improvement occasionally occurred following treatment with corticosteroids. The clinical picture was variable and could present as acute retrobulbar optic neuritis, ischemic optic neuropathy, or slowly progressive visual loss. Visual evoked response testing revealed increased latency in two patients and loss of amplitude in two others; a fifth patient had both findings in the involved eye. Despite the variable presentation, the probable pathogenesis in all cases is vaso-occlusive disease in small vessels of the optic nerves.
我们报告了7例系统性红斑狼疮相关性视神经病变的病例数据。视觉预后各不相同，但使用皮质类固醇治疗后偶尔会有所改善。临床表现多样，可表现为急性球后视神经炎、缺血性视神经病变或缓慢进展的视力丧失。视觉诱发电位测试显示，2例患者潜伏期延长，另2例患者波幅降低；第5例患者患眼同时出现这两种表现。尽管表现各异，但所有病例可能的发病机制均为视神经小血管的血管闭塞性疾病。
