Barkeh H J, Muhaya M
Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, 56000, Cheras, Kuala Lumpur.
Med J Malaysia. 2002 Dec;57(4):490-2.
Systemic lupus erythematosus (SLE) is a common multisystem disorder. However, retinal vasculitis as a primary manifestation of SLE is uncommon, accounting for only 4% of causes of retinal vasculitis. The postulated mechanism appeared to be vaso-occlusion of the retinal arterioles by thrombosis, with resultant ischaemia. Optic neuropathy in SLE is also rare, with a prevalence of 1%. This is a case report of a young lady who presented to us with retinal vasculitis as her initial presentation of SLE. Interestingly, the pathologic mechanism appeared to be inflammatory and not vaso-occlusive.
系统性红斑狼疮（SLE）是一种常见的多系统疾病。然而，视网膜血管炎作为SLE的主要表现并不常见，仅占视网膜血管炎病因的4%。推测的机制似乎是视网膜小动脉因血栓形成而发生血管闭塞，继而导致缺血。SLE相关性视神经病变也很罕见，患病率为1%。本文报告了一位年轻女性患者，她以视网膜血管炎作为SLE的首发表现就诊于我院。有趣的是，其病理机制似乎是炎症性的而非血管闭塞性的。
