Noble A D, Letchworth A T
Postgrad Med J. 1979;55 Suppl 5:37-9.
In a comparison of danazol, and mestranol with norethynodrel (Enavid, Searle) in the treatment of endometriosis danazol was shown to be superior. Danazol is however relatively ineffective when large tumours or extensive adhesions are present and such patients will usually need a surgical operation. Women who have completed their families and who have severe symptoms will be better treated by hysterectomy. Treatment with danazol is indicated for young women with mild or moderate endometriosis. Danazol treatment may also be given postoperatively after conservative operations.
在一项比较达那唑、炔雌醇甲醚与异炔诺酮（炔诺酮，先灵葆雅公司生产）治疗子宫内膜异位症效果的研究中，结果显示达那唑更具优势。然而，当存在大的肿瘤或广泛粘连时，达那唑相对无效，这类患者通常需要进行外科手术。已完成生育且症状严重的女性，行子宫切除术治疗效果更佳。达那唑治疗适用于患有轻度或中度子宫内膜异位症的年轻女性。达那唑治疗也可在保守手术后进行。
