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一种治疗难治性尾骨痛的新方法:超声-荧光透视引导下的骶尾神经冷冻消融术

A novel approach to refractory coccydynia: ultrasound- fluoroscopy-guided cryoablation of sacrococcygeal nerve.

作者信息

Mendes-Andrade Inês, Pagan-Rosado Robert, Ferreira-Silva Nuno, Hurdle Mark Friedrich

机构信息

Department of Physical Medicine and Rehabilitation, Rehabilitation Medicine Center of Alcoitão, Lisbon, Portugal.

Department of Pain Medicine, Mayo Clinic, Jacksonville, FL, USA.

出版信息

Pain Manag. 2024 Oct-Nov;14(10-11):541-547. doi: 10.1080/17581869.2024.2430162. Epub 2024 Nov 17.

DOI:10.1080/17581869.2024.2430162
PMID:39552215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11622740/
Abstract

Coccydynia, also termed chronic pain in the tailbone, is a complex condition with limited treatment options for refractory cases. This case series introduces a novel approach for treating refractory coccydynia using cryoablation of the sacrococcygeal nerves under combined ultrasound and fluoroscopy guidance. Two female patients, suffering from chronic pain for over six months and unresponsive to conservative interventions, underwent cryoablation. Both patients reported significant pain relief, with more than 50% reduction in their numeric rating scale scores, and no major complications were observed during or after the procedure. Furthermore, we propose a clinical treatment algorithm to assist in selecting appropriate interventions for refractory coccydynia, based on the anatomical source of the pain. The findings suggest that cryoablation may be a valuable option for patients with persistent coccygeal pain; however, larger prospective studies are required to confirm its efficacy and long-term safety.

摘要

尾骨痛,也称为慢性尾骨疼痛,是一种复杂的病症,对于难治性病例的治疗选择有限。本病例系列介绍了一种在超声和荧光透视联合引导下使用骶尾神经冷冻消融治疗难治性尾骨痛的新方法。两名女性患者,患有慢性疼痛超过六个月且对保守干预无反应,接受了冷冻消融治疗。两名患者均报告疼痛明显缓解,数字评分量表得分降低超过50%,且在手术期间或术后未观察到重大并发症。此外,我们提出了一种临床治疗算法,以根据疼痛的解剖来源协助为难治性尾骨痛选择合适的干预措施。研究结果表明,冷冻消融可能是持续性尾骨疼痛患者的一种有价值的选择;然而,需要更大规模的前瞻性研究来证实其疗效和长期安全性。

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Histopathologic Study of the Effects of Surgically Applied Cryoanalgesia on Intercostal Nerves in a Live Porcine Model.在活猪模型中,手术应用冷冻镇痛对肋间神经影响的组织病理学研究。
J Clin Med. 2024 Jun 4;13(11):3304. doi: 10.3390/jcm13113304.
2
Ultrasound-Guided Coccygeal Nerve Radiofrequency Ablation and Steroid Injection: Combination Therapy for Coccydynia.超声引导下尾骨神经射频消融联合类固醇注射:尾痛症的联合治疗。
J Ultrasound Med. 2024 Jan;43(1):57-64. doi: 10.1002/jum.16334. Epub 2023 Sep 14.
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The Impact of Local Corticosteroid Administration on the Incidence of Post-Neurotomy Neuritis: A Prospective Investigation.局部皮质类固醇给药对神经切断术后神经炎发生率的影响:一项前瞻性研究。
Pain Physician. 2022 Jan;25(1):E121-E126.
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Percutaneous cryoneurolysis for acute pain management: current status and future prospects.经皮冷冻神经松解术治疗急性疼痛管理:现状与展望。
Expert Rev Med Devices. 2021 Jun;18(6):533-543. doi: 10.1080/17434440.2021.1927705. Epub 2021 May 17.
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Coccydynia-A comprehensive review on etiology, radiological features and management options.尾骨痛——关于病因、放射学特征及治疗选择的综合综述
J Clin Orthop Trauma. 2021 Jan;12(1):123-129. doi: 10.1016/j.jcot.2020.09.025. Epub 2020 Sep 24.
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Pain Physician. 2019 Jan;22(1):69-74.
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