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乳房缩小术患者使用消遣性大麻的情况:特征、并发症及术后即刻镇痛需求

The Use of Recreational Cannabis Among Breast Reduction Patients: Characteristics, Complications, and Immediate Postoperative Analgesic Needs.

作者信息

Shamamian Peter E, Kwon Daniel Y, Oleru Olachi, Seyidova Nargiz, Kim Esther, Genet Simeret, Gyasi Abena, Wang Carol Y, Henderson Peter W

机构信息

Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Plast Surg (Oakv). 2024 Aug 30:22925503241276549. doi: 10.1177/22925503241276549.

Abstract

The characteristics, complications, and postoperative analgesic needs of patients with a recent or active history of recreational cannabis use have not been explored explicitly in plastic surgery. In this study, the characteristics, complications, and postoperative analgesic needs within a population of breast reduction patients who use and do not use recreational cannabis were compared. A retrospective cohort study was carried out on patients who underwent breast reduction between 2019 and 2023. Demographics, comorbidities, recreational cannabis use, postoperative opioid use, and postoperative complications were collected. Patients with a recent history (<1 month since last cannabis use) or current cannabis use were then compared to patients with no history of cannabis use. In total, 340 patients were included, 88 (26%) patients had a history of cannabis use and 252 (74%) did not. Patients in the cannabis-using group were significantly younger than in the non-cannabis-using group (28 years vs 40 years,  < .01), and significantly more patients in the non-cannabis group had hypertension (20% vs 6%  < .01). More patients in the cannabis-using group had hematomas (5% vs 1%,  = .041) and fewer had t-point breakdown (4% vs 0%,  = .046), but these figures lost statistical significance on multiple logistic regression analysis after controlling for possible confounding factors including demographics and comorbidities ( > .05). There were no significant differences in proportions of opioid use or by doses of opioids, even when converted to oral morphine equivalents ( > .05). The analgesic needs, postoperative pain levels, and complications between cannabis-using and non-cannabis-using cohorts were similar. Counseling on substance use preoperatively should still be encouraged, especially in younger patients seeking reduction mammaplasty.

摘要

整形手术中,近期有吸食消遣性大麻或有吸食消遣性大麻活动史的患者的特征、并发症及术后镇痛需求尚未得到明确研究。在本研究中,对使用和不使用消遣性大麻的缩乳患者群体的特征、并发症及术后镇痛需求进行了比较。对2019年至2023年间接受缩乳手术的患者进行了一项回顾性队列研究。收集了人口统计学数据、合并症、消遣性大麻使用情况、术后阿片类药物使用情况及术后并发症。然后将近期有大麻使用史(自上次使用大麻以来<1个月)或当前使用大麻的患者与无大麻使用史的患者进行比较。总共纳入了340例患者,其中88例(26%)有大麻使用史,252例(74%)没有。使用大麻组的患者明显比不使用大麻组的患者年轻(28岁对40岁,P<0.01),不使用大麻组中患高血压的患者明显更多(20%对6%,P<0.01)。使用大麻组中出现血肿的患者更多(5%对1%,P=0.041),出现T点破裂的患者更少(4%对0%,P=0.046),但在控制了包括人口统计学和合并症在内的可能混杂因素后,这些数字在多因素逻辑回归分析中失去了统计学意义(P>0.05)。阿片类药物使用比例或阿片类药物剂量方面没有显著差异,即使转换为口服吗啡等效剂量也是如此(P>0.05)。使用大麻和不使用大麻队列之间的镇痛需求、术后疼痛水平及并发症相似。仍应鼓励在术前进行药物使用咨询,尤其是在寻求缩乳手术的年轻患者中。

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