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中毒性休克综合征作为小儿门诊烧伤治疗中一种意外并发症:病例回顾

Toxic Shock Syndrome as an Unexpected Complication in Outpatient Pediatric Burn Treatment: A Chart Review.

作者信息

Sirajee Reshma, Baykan Altay, Fraulin Frankie O G, Cawthorn Thomas, Sass Kimberly, Harrop Alan Robertson, Hartley Rebecca L, McPhalen Donald Ford

机构信息

Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Section of Pediatric Surgery, Alberta Children's Hospital, Calgary, Alberta, Canada.

出版信息

Plast Surg (Oakv). 2024 Apr 28:22925503241249758. doi: 10.1177/22925503241249758.

DOI:10.1177/22925503241249758
PMID:39553534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11562230/
Abstract

Minor burn injuries in children affecting less than 10% of total body surface area (TBSA) are often successfully managed in the outpatient setting, however it is important to recognize they can be associated with serious sequelae such as toxic shock syndrome (TSS). We conducted a retrospective chart review at a tertiary-level pediatric hospital between May 2012 and May 2022 to identify pediatric patients diagnosed with TSS following minor burn injuries. Data collected included: patient demographics, burn characteristics, TSS symptoms, and management. Data was analyzed using descriptive statistics. During the study period, 3706 patients with minor burns were treated as outpatients, of which 6 patients developed TSS. Ages ranged from 12 to 36 months, and half were male. Most injuries were scalds (n = 4) or contact injuries (n = 2), involving 1% to 3% TBSA partial-thickness burns. Early symptoms of TSS included vomiting (n = 6) and fever (n = 5), and later, hypotension (n = 5). Hospital admission for TSS occurred 1 to 6 days post-injury. Four of the 6 patients required ICU care, with 2 of them requiring fluid resuscitation and 2 receiving IVIg. The clinical course of 2 patients was complicated by deep vein thrombosis, with 1 patient developing a septic ileus as a secondary infection. All patients recovered and were discharged home after 3 to 9 days. We highlight the rare complication of TSS following minor burns in children. Providers should be vigilant for early symptoms of TSS like fever, vomiting, and hypotension. Further research to identify at-risk patients and preventative treatment would be beneficial.

摘要

儿童轻度烧伤面积小于全身表面积(TBSA)的10%时,通常可在门诊成功处理,然而,必须认识到这些烧伤可能会引发严重后遗症,如中毒性休克综合征(TSS)。我们在一家三级儿科医院进行了一项回顾性病历审查,时间跨度为2012年5月至2022年5月,以确定轻度烧伤后被诊断为TSS的儿科患者。收集的数据包括:患者人口统计学资料、烧伤特征、TSS症状及治疗情况。使用描述性统计方法对数据进行分析。在研究期间,3706例轻度烧伤患者接受了门诊治疗,其中6例发生了TSS。年龄范围为12至36个月,半数为男性。大多数损伤为烫伤(n = 4)或接触性损伤(n = 2),涉及1%至3%TBSA的浅度烧伤。TSS的早期症状包括呕吐(n = 6)和发热(n = 5),随后出现低血压(n = 5)。TSS导致的住院发生在受伤后1至6天。6例患者中有4例需要重症监护,其中2例需要液体复苏,2例接受静脉注射免疫球蛋白。2例患者的临床病程因深静脉血栓形成而复杂化,1例患者继发感染出现感染性肠梗阻。所有患者均康复,3至9天后出院。我们强调了儿童轻度烧伤后发生TSS这种罕见并发症。医疗人员应警惕TSS的早期症状,如发热、呕吐和低血压。进一步研究以确定高危患者和预防性治疗将是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/fd0a6bb1c276/10.1177_22925503241249758-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/9ae3b1484929/10.1177_22925503241249758-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/885287d0cc37/10.1177_22925503241249758-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/fd0a6bb1c276/10.1177_22925503241249758-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/9ae3b1484929/10.1177_22925503241249758-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/885287d0cc37/10.1177_22925503241249758-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0f4/12437233/fd0a6bb1c276/10.1177_22925503241249758-fig3.jpg

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本文引用的文献

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Plast Reconstr Surg Glob Open. 2020 Mar 25;8(3):e2703. doi: 10.1097/GOX.0000000000002703. eCollection 2020 Mar.
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Pediatric Toxic Shock Syndrome After a 7% Burn: A Case Study and Systematic Literature Review.
儿童 7%烧伤后中毒性休克综合征:病例研究和系统文献回顾。
Ann Plast Surg. 2020 Jan;84(1):35-42. doi: 10.1097/SAP.0000000000001990.
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Streptococcal toxic shock syndrome in the intensive care unit.重症监护病房中的链球菌中毒性休克综合征
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