• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

对经历激光加热和消融的生物组织的热机械性能进行原位实时监测。

In-situ, real-time monitoring of thermo-mechanical properties of biological tissues undergoing laser heating and ablation.

作者信息

Kurbanova Bayan, Alisherov Shakhrizat, Ashikbayeva Zhannat, Katrenova Zhanerke, Sametova Akbota, Gaipov Abduzhappar, Molardi Carlo, Blanc Wilfried, Tosi Daniele, Utegulov Zhandos

机构信息

Department of Physics, School of Sciences and Humanities, Nazarbayev University, 010000 Astana, Kazakhstan.

Department of Electrical and Computer Engineering, School of Engineering and Digital Sciences, Nazarbayev University, 010000 Astana, Kazakhstan.

出版信息

Biomed Opt Express. 2024 Oct 4;15(11):6198-6210. doi: 10.1364/BOE.537374. eCollection 2024 Nov 1.

DOI:10.1364/BOE.537374
PMID:39553871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11563316/
Abstract

In this work, Brillouin light-scattering spectroscopy and optical backscattering reflectometry (OBR) using Mg-silica-NP-doped distributed sensing fibers were employed for monitoring local GHz visco-elastic properties and surface temperature, respectively, laser driven heating and ablation of chicken tissues. The spatial temperature distribution measured by OBR at various infrared laser heating powers and times was used to validate spatio-temporal local temperature variations modeled by the finite element method via solving Pennes' bioheat conduction equation. The reduction of viscosity and stiffness in chicken skin during its laser heating was attributed to water loss, protein denaturation and change in lipid phase behavior. These findings open avenues for the simultaneous real-time hybrid optical sensing of both viscoelasticity and local temperature in biological tissues undergoing denaturation and gelation during thermal ablation in clinical settings.

摘要

在这项工作中，使用掺镁二氧化硅纳米粒子的分布式传感光纤的布里渊光散射光谱和光学背向散射反射测量法（OBR）分别用于监测鸡组织的局部吉赫兹粘弹性特性和表面温度、激光驱动的加热和消融。通过OBR在各种红外激光加热功率和时间下测量的空间温度分布，用于通过求解彭尼斯生物热传导方程来验证由有限元方法建模的时空局部温度变化。鸡皮在激光加热过程中粘度和刚度的降低归因于水分流失、蛋白质变性和脂质相行为的变化。这些发现为临床环境中热消融期间经历变性和凝胶化的生物组织中的粘弹性和局部温度的同步实时混合光学传感开辟了道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/32c24f5ac137/boe-15-11-6198-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/1d30f9414217/boe-15-11-6198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/e01677f97577/boe-15-11-6198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/90832ea75c44/boe-15-11-6198-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/b71e464abfeb/boe-15-11-6198-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/18ecbbbdfc57/boe-15-11-6198-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/6fba941f4cfc/boe-15-11-6198-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/68803d6e798a/boe-15-11-6198-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/32c24f5ac137/boe-15-11-6198-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/1d30f9414217/boe-15-11-6198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/e01677f97577/boe-15-11-6198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/90832ea75c44/boe-15-11-6198-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/b71e464abfeb/boe-15-11-6198-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/18ecbbbdfc57/boe-15-11-6198-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/6fba941f4cfc/boe-15-11-6198-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/68803d6e798a/boe-15-11-6198-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fb/11563316/32c24f5ac137/boe-15-11-6198-g008.jpg

相似文献

1
In-situ, real-time monitoring of thermo-mechanical properties of biological tissues undergoing laser heating and ablation.对经历激光加热和消融的生物组织的热机械性能进行原位实时监测。
Biomed Opt Express. 2024 Oct 4;15(11):6198-6210. doi: 10.1364/BOE.537374. eCollection 2024 Nov 1.
2
Thermo-Visco-Elastometry of RF-Wave-Heated and Ablated Flesh Tissues Containing Au Nanoparticles.射频加热和烧蚀含金纳米粒子的肉组织的热粘弹计量学。
Biosensors (Basel). 2022 Dec 22;13(1):8. doi: 10.3390/bios13010008.
3
Thermal wave and Pennes' models of bioheat transfer in human skin: A transient comparative analysis.人体皮肤生物热传递的热波模型和彭尼斯模型：瞬态对比分析
Heliyon. 2024 Nov 2;10(21):e40109. doi: 10.1016/j.heliyon.2024.e40109. eCollection 2024 Nov 15.
4
Towards real-time finite-strain anisotropic thermo-visco-elastodynamic analysis of soft tissues for thermal ablative therapy.用于热消融治疗的软组织实时有限应变各向异性热粘弹动力学分析
Comput Methods Programs Biomed. 2021 Jan;198:105789. doi: 10.1016/j.cmpb.2020.105789. Epub 2020 Oct 8.
5
Monitoring of tissue optical properties during thermal coagulation of ex vivo tissues.体外组织热凝固过程中组织光学特性的监测。
Lasers Surg Med. 2016 Sep;48(7):686-94. doi: 10.1002/lsm.22541. Epub 2016 Jun 1.
6
Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion.具有空间异质性、温度依赖性灌注的皮肤热传输的传输晶格模型。
Biomed Eng Online. 2004 Nov 17;3(1):42. doi: 10.1186/1475-925X-3-42.
7
Multi-fiber distributed thermal profiling of minimally invasive thermal ablation with scattering-level multiplexing in MgO-doped fibers.在掺氧化镁光纤中利用散射级复用对微创热消融进行多光纤分布式热剖析
Biomed Opt Express. 2019 Feb 19;10(3):1282-1296. doi: 10.1364/BOE.10.001282. eCollection 2019 Mar 1.
8
Temperature-controlled power modulation compensates for heterogeneous nanoparticle distributions: a computational optimization analysis for magnetic hyperthermia.温度控制功率调制补偿不均匀纳米粒子分布：磁热疗的计算优化分析。
Int J Hyperthermia. 2019;36(1):115-129. doi: 10.1080/02656736.2018.1538538. Epub 2018 Dec 12.
9
Transient bioheat simulation of the laser-tissue interaction in human skin using hybrid finite element formulation.使用混合有限元公式对人体皮肤中激光与组织相互作用进行瞬态生物热模拟。
Mol Cell Biomech. 2012 Mar;9(1):31-53.
10
[Temperature distribution based on Monte Carlo method of optical transmission in tissues of laser ablation].基于蒙特卡罗方法的激光消融组织中光传输的温度分布
Zhongguo Yi Liao Qi Xie Za Zhi. 2013 Jul;37(4):252-4, 280.

本文引用的文献

1
Brillouin Biosensing of Viscoelasticity across Phase Transitions in Ovine Cornea.羊眼角膜相变过程中的粘弹性的布里渊生物传感研究。
Biosensors (Basel). 2024 Jul 30;14(8):371. doi: 10.3390/bios14080371.
2
Mechano-Chemistry across Phase Transitions in Heated Albumin Protein Solutions.加热白蛋白溶液中跨相变的机械化学
Polymers (Basel). 2023 Apr 25;15(9):2039. doi: 10.3390/polym15092039.
3
Thermo-Visco-Elastometry of RF-Wave-Heated and Ablated Flesh Tissues Containing Au Nanoparticles.射频加热和烧蚀含金纳米粒子的肉组织的热粘弹计量学。
Biosensors (Basel). 2022 Dec 22;13(1):8. doi: 10.3390/bios13010008.
4
Mechano-Chemical Properties of Electron Beam Irradiated Polyetheretherketone.电子束辐照聚醚醚酮的机械化学性质
Polymers (Basel). 2022 Jul 29;14(15):3067. doi: 10.3390/polym14153067.
5
Thermo-vibrational analyses of skin tissue subjected to laser heating source in thermal therapy.热疗中激光加热源作用下皮肤组织的热-振动分析。
Sci Rep. 2021 Nov 19;11(1):22633. doi: 10.1038/s41598-021-02006-7.
6
Refractive index of biological tissues: Review, measurement techniques, and applications.生物组织的折射率：综述、测量技术及应用
Photodiagnosis Photodyn Ther. 2021 Mar;33:102192. doi: 10.1016/j.pdpdt.2021.102192. Epub 2021 Jan 27.
7
Time-resolved Assessment of Drying Plants by Brillouin and Raman Spectroscopies.利用布里渊光谱和拉曼光谱对干燥植物进行时间分辨评估。
J Raman Spectrosc. 2019 Dec;50(12):1881-1889. doi: 10.1002/jrs.5742. Epub 2019 Sep 15.
8
Development and validation of hybrid Brillouin-Raman spectroscopy for non-contact assessment of mechano-chemical properties of urine proteins as biomarkers of kidney diseases.发展和验证布里渊-拉曼光谱杂交技术，用于非接触式评估尿液蛋白质的机械化学性质，作为肾脏疾病生物标志物。
BMC Nephrol. 2020 Jun 15;21(1):229. doi: 10.1186/s12882-020-01890-x.
9
Characterisation of Ex Vivo Liver Thermal Properties for Electromagnetic-Based Hyperthermic Therapies.用于电磁热疗的离体肝脏热特性分析。
Sensors (Basel). 2020 May 25;20(10):3004. doi: 10.3390/s20103004.
10
Analytical estimations of temperature in a living tissue generated by laser irradiation using experimental data.利用实验数据对激光辐照活体组织产生的温度进行分析估算。
J Therm Biol. 2019 Oct;85:102421. doi: 10.1016/j.jtherbio.2019.102421. Epub 2019 Sep 20.