Choudhury Arghya Kundu, Gupta Kshitij, Regmi Anil, Niraula Bishwa Bandhu, Sharma Divyansh, Gupta Tushar, Kalia Roop Bhushan
Centre of Robotics and Joint Replacement Surgery, Sarvodaya Hospital and Research Centre, Faridabad, India.
Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, India.
J Clin Orthop Trauma. 2024 Oct 29;58:102794. doi: 10.1016/j.jcot.2024.102794. eCollection 2024 Nov.
Total knee arthroplasty is the commonest procedure being done for Osteoarthritis of knee in current practice. In spite of its success many patients suffer from post-operative pain especially in the early post-operative period. The study aimed to evaluate the pain relief and functional benefit of periarticular cocktail infiltration.
Sixty-four patients undergoing simultaneous bilateral total knee were randomised to receive peri-articular cocktail injection in one knee and a similar amount of normal saline in contralateral knee. Cocktail consisted of ketorolac, ropivacaine and epinephrine. Patients' visual analog pain score (VAS), knee range of motion, quadriceps strength, single step test (SST) were recorded post-operatively.
The cocktail infiltrated knee had significantly lesser pain scores during the first 48 h. Intervened knee achieved better knee range of motion at 72 h and 14 days post-surgery. Quadriceps power and SST had better results in cocktail injected knees at 72 h, but no significant difference was detected at 14-day follow-up.
Use of peri-articular cocktail injection is an effective modality to achieve better pain relief in early post-operative period. Though the benefits are not long lived, but its superior effects can be utilised for early functional recovery after TKA and improved patient rehabilitation.
I, Randomized Controlled Trial.
全膝关节置换术是目前治疗膝关节骨关节炎最常见的手术。尽管取得了成功，但许多患者术后仍会遭受疼痛，尤其是在术后早期。本研究旨在评估关节周围鸡尾酒式注射的止痛效果和功能益处。
64例同时接受双侧全膝关节置换术的患者被随机分为两组，一组在一侧膝关节接受关节周围鸡尾酒式注射，另一侧膝关节注射等量生理盐水。鸡尾酒式注射药物由酮咯酸、罗哌卡因和肾上腺素组成。术后记录患者的视觉模拟疼痛评分（VAS）、膝关节活动范围、股四头肌力量、单步试验（SST）。
接受鸡尾酒式注射的膝关节在术后48小时内疼痛评分明显较低。在术后72小时和14天时，接受干预的膝关节膝关节活动范围更佳。在术后72小时时，接受鸡尾酒式注射的膝关节股四头肌力量和单步试验结果更好，但在14天随访时未发现显著差异。
关节周围鸡尾酒式注射是一种有效的方法，可在术后早期更好地缓解疼痛。虽然这种益处持续时间不长，但其卓越效果可用于全膝关节置换术后的早期功能恢复及改善患者康复情况。
I，随机对照试验。
