Eaddy Isabel C, Moushmoush Obadah, Sabbagh Omar, Barazi Muhi Dean, Sabbagh Osama
Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
MedStar Georgetown University Hospital, Ophthalmology, Washington, DC, USA.
J Vitreoretin Dis. 2024 May 31;9(1):105-108. doi: 10.1177/24741264241255589. eCollection 2025 Jan-Feb.
To examine the risks associated with the use of pilocarpine hydrochloride 1.25% ophthalmic solution prescribed for presbyopia. The adverse ocular events reported after the use of pilocarpine were compared with the symptoms experienced by a 62-year-old presbyopic man shortly after he took pilocarpine. Soon after instilling pilocarpine, the patient reported symptoms, including eye pain, hazy vision, and floaters. An examination showed a horseshoe retinal tear, vitreous hemorrhage, and posterior vitreous detachment, for which the patient received extensive clinical and surgical management. This case highlights the need for comprehensive eye examinations and patient education about the warning signs of retinal tears or detachments before prescribing pilocarpine for presbyopia. Vigilance regarding the potential rare adverse effects of this new pilocarpine ophthalmic solution is warranted.
为研究使用1.25%盐酸毛果芸香碱眼药水治疗老花眼的相关风险。将使用毛果芸香碱后报告的不良眼部事件与一名62岁老花眼男性服用毛果芸香碱后不久出现的症状进行比较。滴入毛果芸香碱后不久，患者报告出现眼痛、视力模糊和飞蚊症等症状。检查发现马蹄形视网膜裂孔、玻璃体积血和玻璃体后脱离，患者接受了广泛的临床和手术治疗。该病例凸显了在为老花眼开毛果芸香碱处方前，进行全面眼部检查以及对患者进行视网膜裂孔或脱离警示标志教育的必要性。对于这种新型毛果芸香碱眼药水潜在的罕见不良反应需保持警惕。
