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一种规定的植物性饮食和其他综合疗法可改善心力衰竭患者的功能状态和射血分数,同时减少用药:病例系列研究

A Defined, Plant-Based Diet and Other Integrative Therapies Improve Functional Status and Ejection Fraction while Reducing Medications in Patients With Heart Failure: A Case Series.

作者信息

Owens Camille V, Najjar Rami S, Bruce Marino A, Beech Bettina M, Montgomery Baxter D

机构信息

Montgomery Heart & Wellness Center, Houston, TX, USA.

Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.

出版信息

Am J Lifestyle Med. 2024 Sep 6:15598276241281475. doi: 10.1177/15598276241281475.

Abstract

Heart failure with reduced ejection fraction (HFrEF) is a major contributor of premature cardiovascular-related deaths. Patients are typically on numerous medications to manage this condition; however, patients continue to experience poor quality of life. Alternative therapeutic approaches are needed to treat HFrEF. The clinical course of seven patients with Stage C and D HFrEF who failed guideline-directed medical therapy were retrospectively analyzed based on medical chart data. All patients consumed a defined, plant-based diet as part of their clinical treatment, and a subset also underwent alternative treatment modalities: External Counterpulsation therapy, BEMER therapy, infrared sauna therapy, ozone therapy, or PlaqueX® therapy. Chart review of these patients indicated improvement in left ventricular ejection fraction (LVEF) and right ventricular systolic pressure (RVSP). All patients also had a significant reduction in medication needs and body weight. Further, all patients reported significant improvements in their quality of life. These data suggest that a defined, plant-based diet combined with other alternative modalities may be efficacious in reducing HFrEF medications and treating Stage C or D HFrEF patients who failed guideline-direct medical therapies. Observations from this case series indicate a need for rigorous prospective studies to confirm these effects.

摘要

射血分数降低的心力衰竭(HFrEF)是心血管相关过早死亡的主要原因。患者通常需要服用多种药物来控制这种疾病;然而,患者的生活质量仍然很差。需要其他治疗方法来治疗HFrEF。基于病历数据,对7例C期和D期HFrEF且标准药物治疗无效的患者的临床病程进行了回顾性分析。所有患者均采用特定的植物性饮食作为临床治疗的一部分,部分患者还接受了其他治疗方式:体外反搏治疗、BEMER治疗、红外线桑拿治疗、臭氧治疗或PlaqueX®治疗。对这些患者的病历审查表明,左心室射血分数(LVEF)和右心室收缩压(RVSP)有所改善。所有患者的药物需求和体重也显著降低。此外,所有患者均报告生活质量有显著改善。这些数据表明,特定的植物性饮食与其他替代方式相结合,可能对减少HFrEF药物使用以及治疗标准药物治疗无效的C期或D期HFrEF患者有效。该病例系列的观察结果表明,需要进行严格的前瞻性研究来证实这些效果。

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