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英国制药行业向医疗专业组织的付款:对2015年至2021年英国披露数据库的七年横断面分析。

Pharmaceutical industry payments to healthcare professional organisations in the United Kingdom: a seven-year cross-sectional analysis of the Disclosure UK database from 2015 to 2021.

作者信息

Murayama Anju, Fabbri Alice, Scholfield Hannah, Ozieranski Piotr

机构信息

Department of Social and Policy Sciences, Centre for the Analysis of Social Policy, University of Bath, Bath BA2 7AY, UK.

Tohoku University School of Medicine, Sendai, Miyagi 980-0872, Japan.

出版信息

J R Soc Med. 2025 Jan;118(1):16-25. doi: 10.1177/01410768241297441. Epub 2024 Nov 18.

Abstract

OBJECTIVES

This study aimed to examine the size and trends in payments from the pharmaceutical industry to healthcare professional organisations (HPOs) in the United Kingdom (UK), and to characterise the conflict of interest (COI) management plans by HPOs who received large payments.

DESIGN

Cross-sectional analysis of non-research payments disclosed in the Disclosure UK database from 2015 to 2021.

SETTING

United Kingdom.

PARTICIPANTS

148 pharmaceutical companies disclosing payment data and HPOs receiving the largest payments.

MAIN OUTCOME MEASURES

Total value and median of payments per HPO; existence and content of COI policies among HPOs receiving the largest payments.

RESULTS

A total of 898 HPOs received non-research payments worth £99.9 million (17.4% of non-research payments to all healthcare organisations). The median seven-year payment per HPO was £4509 (interquartile range: £943-£30,360). The annual payments nearly doubled from £9.3 million in 2015 to £17.6 million in 2021. Event payments constituted the largest share (£68.2 million, 68.2%). HPOs representing physicians received over 91.5% (£91.5 million) of all payments, while those related to endocrinology and diabetology - 16.3% (£16.3 million). Over 59.9% (£59.9 million) went to the 30 top-funded HPOs, of which only 17 (56.7%) had a publicly accessible COI policy. However, just 6 (35.3%) of these policies included provisions for payments from external organisations.

CONCLUSIONS

HPOs received nearly one-fifth of pharmaceutical company payments to the UK healthcare sector. These payments were concentrated among a small number of HPOs, which often lacked effective policies for management of COI and payments from the industry.

摘要

目的

本研究旨在调查制药行业向英国医疗保健专业组织(HPOs)支付款项的规模和趋势,并描述接受大额付款的HPOs的利益冲突(COI)管理计划。

设计

对2015年至2021年英国披露数据库中披露的非研究付款进行横断面分析。

背景

英国。

参与者

148家披露付款数据的制药公司和接受最大付款的HPOs。

主要观察指标

每个HPO的付款总额和中位数;接受最大付款的HPOs中COI政策的存在情况和内容。

结果

共有898个HPOs收到了价值9990万英镑的非研究付款(占向所有医疗保健组织非研究付款的17.4%)。每个HPO七年付款的中位数为4509英镑(四分位间距:943 - 30360英镑)。年度付款从2015年的930万英镑几乎翻了一番,增至2021年的1760万英镑。活动付款占比最大(6820万英镑,68.2%)。代表医生的HPOs收到了所有付款的91.5%以上(9150万英镑),而与内分泌学和糖尿病学相关的HPOs收到了16.3%(1630万英镑)。超过59.9%(5990万英镑)流向了30个获得资金最多的HPOs中,其中只有17个(56.7%)有公开可用的COI政策。然而,这些政策中只有6个(35.3%)包括了来自外部组织付款的规定。

结论

HPOs收到了制药公司向英国医疗保健部门付款的近五分之一。这些付款集中在少数HPOs中,而这些HPOs往往缺乏有效的COI管理政策和行业付款管理政策。

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