念珠菌属菌株对五种抗真菌药物的敏感性：琼脂稀释法与纸片扩散法的比较
Susceptibility of Candida species strains to five antifungal agents: comparison between agar dilution and disk diffusion tests.
作者信息
Trancassini M, Ghezzi M C, Cipriani P, Mancini C, Brenciaglia M I
出版信息
Chemioterapia. 1986 Feb;5(1):14-7.
The in vitro activity of five antifungal agents were compared against 180 Candida strains. The drugs were: two imidazoles (miconazole and ketoconazole), nystatin, 5-fluorocytosine and amphotericin B. Agar dilution and disk diffusion methods were used. Nystatin, miconazole and amphotericin B were the most active agents. 5-fluorocytosine had high activity except against C. albicans serotype B, of which a high percentage were resistant. Finally, a good correlation between the two methods was observed.
比较了五种抗真菌药物对180株念珠菌的体外活性。这些药物分别是：两种咪唑类药物（咪康唑和酮康唑）、制霉菌素、5-氟胞嘧啶和两性霉素B。采用了琼脂稀释法和纸片扩散法。制霉菌素、咪康唑和两性霉素B是活性最强的药物。5-氟胞嘧啶除了对B型白色念珠菌活性高外，对其大部分菌株都有耐药性。最后，观察到两种方法之间有良好的相关性。
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