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年轻成年人的ABO血型与听觉功能

ABO Blood Group and Auditory Function in Young Adults.

作者信息

Varghese Liya, C S Swathi

机构信息

Department of Audiology and Speech Language Pathology, AWH Special college, Kallai, Calicut, Kerala India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5596-5601. doi: 10.1007/s12070-024-05039-2. Epub 2024 Sep 16.

Abstract

INTRODUCTION

In recent years, research on the effect of blood group on hearing function has gained more attention. Some blood groups show susceptibility to certain general health and auditory disorders like noise induced hearing loss, infections, coronary artery disease, gastric carcinoma and duodenal ulcer.

AIMS

The present study aimed to determine the differences in middle ear and cochlear function among persons with different blood groups (AB, A, B, O).

MATERIALS AND METHODS

Sixty adults (18-24 years) with normal hearing sensitivity were included in the study. They were divided into four groups based on blood groups (A, B, AB, O) with 15 participants each. High-frequency thresholds, distortion product otoacoustic emissions (DPOAE) and resonance frequency were measured. High-frequency thresholds for both ears were measured at octave frequencies from 9 kHz to 16 kHz. Resonant frequency was determined using sweep frequency method.

RESULTS

The findings demonstrated that individuals with blood group AB and O had considerably lower DPOAE amplitudes. Resonance frequency and extended high frequency thresholds did not, however, differ significantly between the blood groups.

CONCLUSION

The decrease in the amplitude of otoacoustic emissions (OAE) can be explained by a reduction in the quantity of robust outer hair cells and elevated protein levels, which in turn lead to a reduction in the cochlear blood flow in persons with blood type O and AB, respectively. More research with greater numbers of participants is necessary to improve the generalization of the findings.

摘要

引言

近年来,关于血型对听力功能影响的研究受到了更多关注。一些血型对某些一般健康问题和听觉障碍表现出易感性,如噪声性听力损失、感染、冠状动脉疾病、胃癌和十二指肠溃疡。

目的

本研究旨在确定不同血型(AB型、A型、B型、O型)人群中耳和耳蜗功能的差异。

材料与方法

60名听力敏感度正常的成年人(18 - 24岁)纳入本研究。他们根据血型分为四组(A型、B型、AB型、O型),每组15人。测量高频听阈、畸变产物耳声发射(DPOAE)和共振频率。双耳高频听阈在9kHz至16kHz的倍频程频率下测量。共振频率采用扫频法测定。

结果

研究结果表明,AB型和O型血的个体DPOAE幅值明显较低。然而,血型之间的共振频率和扩展高频听阈没有显著差异。

结论

耳声发射(OAE)幅值的降低可以分别通过O型和AB型血的人强健外毛细胞数量减少和蛋白质水平升高来解释,这进而导致耳蜗血流量减少。需要更多参与者进行更多研究以提高研究结果的普遍性。

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Effect of different blood groups on tympanometric findings and acoustic reflex thresholds.不同血型对鼓室导抗图结果及听反射阈值的影响。
Eur Arch Otorhinolaryngol. 2020 Dec;277(12):3513-3518. doi: 10.1007/s00405-020-06244-9. Epub 2020 Jul 31.
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The characteristic of otoacoustic emissions in full-term neonates according to ABO blood groups.根据 ABO 血型的足月新生儿耳声发射特征。
Braz J Otorhinolaryngol. 2020 Nov-Dec;86(6):774-780. doi: 10.1016/j.bjorl.2019.10.012. Epub 2019 Dec 10.
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Effect of Blood Group on Ultrahigh Frequency Auditory Sensitivity.血型对超高频听觉敏感性的影响。
Int Arch Otorhinolaryngol. 2018 Oct;22(4):364-367. doi: 10.1055/s-0037-1613711. Epub 2017 Dec 15.
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Otoacoustic emissions in young adults: Effects of blood group.年轻成年人的耳声发射:血型的影响。
Hear Res. 2016 Mar;333:194-200. doi: 10.1016/j.heares.2015.09.006. Epub 2015 Sep 14.

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