Lalika Mathias, Jenkins Sarah, Hayes Sharonne N, Jones Clarence, Burke Lora E, Cooper Lisa A, Patten Christi A, Brewer LaPrincess C
Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Digit Health. 2024 Nov 17;10:20552076241295305. doi: 10.1177/20552076241295305. eCollection 2024 Jan-Dec.
African Americans have a higher prevalence of cardiovascular risk factors, leading to higher cardiovascular disease mortality than White adults. Our culturally tailored mobile health (mHealth) lifestyle intervention () has previously demonstrated efficacy in promoting ideal cardiovascular health in African Americans.
We conducted a secondary analysis from a cluster randomized controlled trial among African-Americans from 16 churches in Minnesota that compared the to a delayed intervention control group. A subgroup of participants with ≥ 1 diagnosis of overweight/obesity, hyperlipidemia, hypertension, or diabetes was examined. The primary outcome was a change in LS7 score-a measure of cardiovascular health ranging from poor to ideal (range 0-14 points)-at 6-months post-intervention.
The analysis included 49 participants (intervention group: = 20; mean age 58.8 years, 75% female; control group: = 29, mean age 52.5 years, 76% female) with no significant baseline differences in cardiovascular risk factors. Compared to the control group, the intervention group showed a greater increase in LS7 score across all cardiovascular risk factors at 6-months post-intervention, with statistically significant differences among those with overweight/obesity (intervention effect 1.77, < 0.0001) and 2+ or 3+ cardiovascular risk factors (1.00, = 0.03; 1.09, = 0.04). The intervention group demonstrated a higher increase in the percentage of participants with intermediate or ideal LS7 scores than the control group, although these differences were not statistically significant.
Our culturally tailored mHealth lifestyle intervention was associated with significant increases in LS7 scores among African Americans with preexisting cardiovascular risk factors, suggesting its efficacy in improving cardiovascular health among this population.
非裔美国人心血管危险因素的患病率较高，导致其心血管疾病死亡率高于白人成年人。我们针对文化定制的移动健康（mHealth）生活方式干预措施（）此前已证明在促进非裔美国人实现理想心血管健康方面具有成效。
我们对明尼苏达州16所教堂的非裔美国人进行的一项整群随机对照试验进行了二次分析，将该干预措施与延迟干预对照组进行了比较。对有≥1项超重/肥胖、高脂血症、高血压或糖尿病诊断的参与者亚组进行了检查。主要结局是干预后6个月时LS7评分的变化，LS7评分是一种衡量心血管健康的指标，范围从差到理想（0 - 14分）。
分析纳入了49名参与者（干预组： = 20；平均年龄58.8岁，75%为女性；对照组： = 29，平均年龄52.5岁，76%为女性），他们在心血管危险因素方面基线无显著差异。与对照组相比，干预组在干预后6个月时所有心血管危险因素的LS7评分均有更大幅度的增加，在超重/肥胖者（干预效应1.77， < 0.0001）以及有2种或3种以上心血管危险因素者（1.00， = 0.03；1.09， = 0.04）中存在统计学显著差异。干预组中LS7评分处于中等或理想水平的参与者百分比增幅高于对照组，尽管这些差异无统计学显著性。
我们针对文化定制的mHealth生活方式干预措施与已有心血管危险因素的非裔美国人LS7评分显著增加相关，表明其在改善该人群心血管健康方面具有成效。
