Woolhouse M E J
Usher Institute, University of Edinburgh, Charlotte Auerbach Rd, Edinburgh EH9 3FL, UK.
Sci One Health. 2024 Oct 21;3:100082. doi: 10.1016/j.soh.2024.100082. eCollection 2024.
Antimicrobial resistance (AMR) is a significant and growing threat to human health. A recent United Nations General Assembly declaration highlights that those in need must have sustained access to effective treatments. In the absence of a reliable supply of new drugs, pressure on existing drugs can be reduced by minimising demand. Routes to reducing demand include: promotion of WASH (access to clean water, sanitation and hygiene) and Universal Health Coverage (UHC); improved infection control in health care settings; and continued efforts to curtail drug use in agriculture. This is a One Health strategy, requiring coordinated action across the human, livestock and environmental sectors.
抗菌药物耐药性（AMR）对人类健康构成了重大且日益严重的威胁。联合国大会最近的一项宣言强调，有需要的人必须持续获得有效的治疗。在缺乏可靠的新药供应的情况下，可以通过尽量减少需求来减轻现有药物的压力。减少需求的途径包括：推广水、环境卫生和个人卫生（WASH）以及全民健康覆盖（UHC）；改善医疗机构的感染控制；以及继续努力减少农业中的药物使用。这是一项“同一个健康”战略，需要人类、牲畜和环境部门采取协调行动。
