FOXC1 and retinopathy: targeting molecular mechanisms in retinal blood vessel growth.
作者信息
Kume Tsutomu
机构信息
Feinberg Cardiovascular and Renal Research Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
出版信息
Expert Opin Ther Targets. 2024 Dec;28(12):1017-1020. doi: 10.1080/14728222.2024.2432411. Epub 2024 Nov 27.
Abstract
摘要
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本文引用的文献
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Cell and molecular targeted therapies for diabetic retinopathy.糖尿病视网膜病变的细胞和分子靶向治疗。
Front Endocrinol (Lausanne). 2024 Jun 14;15:1416668. doi: 10.3389/fendo.2024.1416668. eCollection 2024.
2
FOXC1 regulates endothelial CD98 (LAT1/4F2hc) expression in retinal angiogenesis and blood-retina barrier formation.FOXC1 在视网膜血管生成和血视网膜屏障形成中调节内皮细胞 CD98（LAT1/4F2hc）的表达。
Nat Commun. 2024 May 16;15(1):4097. doi: 10.1038/s41467-024-48134-2.
3
Assessment of Inner Blood-Retinal Barrier: Animal Models and Methods.内眼血视网膜屏障评估：动物模型与方法。
Cells. 2023 Oct 12;12(20):2443. doi: 10.3390/cells12202443.
4
FoxC1 activates limbal epithelial stem cells following corneal epithelial debridement.FoxC1 可在角膜上皮清创后激活角膜缘上皮干细胞。
Exp Eye Res. 2023 Sep;234:109599. doi: 10.1016/j.exer.2023.109599. Epub 2023 Jul 22.
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Targeting hypoxia-inducible factors with 32-134D safely and effectively treats diabetic eye disease in mice.用 32-134D 靶向缺氧诱导因子安全有效地治疗小鼠的糖尿病眼病。
J Clin Invest. 2023 Jul 3;133(13):e163290. doi: 10.1172/JCI163290.
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Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury.内皮细胞 FOXC1 和 FOXC2 促进缺血再灌注损伤后的肠道再生。
EMBO Rep. 2023 Jul 5;24(7):e56030. doi: 10.15252/embr.202256030. Epub 2023 May 8.
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Beyond VEGF: Targeting Inflammation and Other Pathways for Treatment of Retinal Disease.超越 VEGF：针对炎症和其他途径治疗视网膜疾病。
J Pharmacol Exp Ther. 2023 Jul;386(1):15-25. doi: 10.1124/jpet.122.001563. Epub 2023 May 4.
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Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy.局部给予的 NOX4 抑制剂 GLX7013114 可有效治疗糖尿病视网膜病变的早期病变事件。
Diabetes. 2023 May 1;72(5):638-652. doi: 10.2337/db22-0515.
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A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth.YAP/TAZ-TEAD 信号模块将血管内皮细胞的营养摄取与血管生成生长联系起来。
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