• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

机器学习模型预测重症患者术后住院时间的可解释性:机器学习模型的开发和评估。

Explainable predictions of a machine learning model to forecast the postoperative length of stay for severe patients: machine learning model development and evaluation.

机构信息

Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympicro 43Gil, Songpagu, Seoul, 05505, Republic of Korea.

Department of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43 Gil, Sonpagu, 05505, Seoul, Republic of Korea.

出版信息

BMC Med Inform Decis Mak. 2024 Nov 20;24(1):350. doi: 10.1186/s12911-024-02755-1.

DOI:10.1186/s12911-024-02755-1
PMID:39563368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11577810/
Abstract

BACKGROUND

Predicting the length of stay in advance will not only benefit the hospitals both clinically and financially but enable healthcare providers to better decision-making for improved quality of care. More importantly, understanding the length of stay of severe patients who require general anesthesia is key to enhancing health outcomes.

OBJECTIVE

Here, we aim to discover how machine learning can support resource allocation management and decision-making resulting from the length of stay prediction.

METHODS

A retrospective cohort study was conducted from January 2018 to October 2020. A total cohort of 240,000 patients' medical records was collected. The data were collected exclusively for preoperative variables to accurately analyze the predictive factors impacting the postoperative length of stay. The main outcome of this study is an analysis of the length of stay (in days) after surgery until discharge. The prediction was performed with ridge regression, random forest, XGBoost, and multi-layer perceptron neural network models.

RESULTS

The XGBoost resulted in the best performance with an average error within 3 days. Moreover, we explain each feature's contribution over the XGBoost model and further display distinct predictors affecting the overall prediction outcome at the patient level. The risk factors that most importantly contributed to the stay after surgery were as follows: a direct bilirubin laboratory test, department change, calcium chloride medication, gender, and diagnosis with the removal of other organs. Our results suggest that healthcare providers take into account the risk factors such as the laboratory blood test, distributing patients, and the medication prescribed prior to the surgery.

CONCLUSION

We successfully predicted the length of stay after surgery and provide explainable models with supporting analyses. In summary, we demonstrate the interpretation with the XGBoost model presenting insights on preoperative features and defining higher risk predictors to the length of stay outcome. Our development in explainable models supports the current in-depth knowledge for the future length of stay prediction on electronic medical records that aids the decision-making and facilitation of the operation department.

摘要

背景

提前预测住院时间不仅对医院的临床和财务有利,还能使医疗保健提供者更好地做出决策,提高护理质量。更重要的是,了解需要全身麻醉的重症患者的住院时间是提高健康结果的关键。

目的

在这里,我们旨在发现机器学习如何支持资源分配管理和决策,从而预测住院时间。

方法

进行了一项回顾性队列研究,时间为 2018 年 1 月至 2020 年 10 月。共收集了 24 万例患者的病历数据。这些数据仅用于术前变量,以准确分析影响术后住院时间的预测因素。本研究的主要结果是分析手术后直至出院的住院时间(以天为单位)。使用岭回归、随机森林、XGBoost 和多层感知机神经网络模型进行预测。

结果

XGBoost 的表现最好,平均误差在 3 天以内。此外,我们解释了每个特征在 XGBoost 模型中的贡献,并进一步展示了影响总体预测结果的不同预测因素在患者水平上的表现。对手术后住院时间最重要的贡献的风险因素如下:直接胆红素实验室检测、科室变动、氯化钙药物、性别和其他器官切除的诊断。我们的研究结果表明,医疗保健提供者应考虑实验室血液检查、患者分配和手术前开的药物等风险因素。

结论

我们成功地预测了手术后的住院时间,并提供了可解释的模型和支持性分析。总的来说,我们通过 XGBoost 模型展示了对术前特征的解释,并确定了与住院时间结果相关的更高风险预测因素,为未来电子病历的住院时间预测提供了深入的知识支持,有助于决策和手术部门的顺利进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/9cc377b4db34/12911_2024_2755_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/11247aa1bc90/12911_2024_2755_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/1f99e2208a36/12911_2024_2755_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/9f803c1f2ce1/12911_2024_2755_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/044d3be3ab5d/12911_2024_2755_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/e5f761648986/12911_2024_2755_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/df8ddfdfed0d/12911_2024_2755_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/301876664010/12911_2024_2755_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/9cc377b4db34/12911_2024_2755_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/11247aa1bc90/12911_2024_2755_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/1f99e2208a36/12911_2024_2755_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/9f803c1f2ce1/12911_2024_2755_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/044d3be3ab5d/12911_2024_2755_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/e5f761648986/12911_2024_2755_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/df8ddfdfed0d/12911_2024_2755_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/301876664010/12911_2024_2755_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdbd/11577810/9cc377b4db34/12911_2024_2755_Fig8_HTML.jpg

相似文献

1
Explainable predictions of a machine learning model to forecast the postoperative length of stay for severe patients: machine learning model development and evaluation.机器学习模型预测重症患者术后住院时间的可解释性:机器学习模型的开发和评估。
BMC Med Inform Decis Mak. 2024 Nov 20;24(1):350. doi: 10.1186/s12911-024-02755-1.
2
Machine learning-enabled prediction of prolonged length of stay in hospital after surgery for tuberculosis spondylitis patients with unbalanced data: a novel approach using explainable artificial intelligence (XAI).机器学习在数据不平衡的情况下预测脊柱结核手术后住院时间延长的预测:一种使用可解释人工智能 (XAI) 的新方法。
Eur J Med Res. 2024 Jul 25;29(1):383. doi: 10.1186/s40001-024-01988-0.
3
Machine learning algorithms for predicting COVID-19 mortality in Ethiopia.用于预测埃塞俄比亚 COVID-19 死亡率的机器学习算法。
BMC Public Health. 2024 Jun 28;24(1):1728. doi: 10.1186/s12889-024-19196-0.
4
Explainable machine learning model for predicting the occurrence of postoperative malnutrition in children with congenital heart disease.用于预测先天性心脏病儿童术后发生营养不良的可解释机器学习模型。
Clin Nutr. 2022 Jan;41(1):202-210. doi: 10.1016/j.clnu.2021.11.006. Epub 2021 Nov 10.
5
Prediction of additional hospital days in patients undergoing cervical spine surgery with machine learning methods.运用机器学习方法预测行颈椎手术患者的额外住院天数。
Comput Assist Surg (Abingdon). 2024 Dec;29(1):2345066. doi: 10.1080/24699322.2024.2345066. Epub 2024 Jun 11.
6
Predicting conversion of ambulatory ACDF patients to inpatient: a machine learning approach.预测门诊颈椎前路椎间盘切除融合术患者转为住院患者:一种机器学习方法。
Spine J. 2024 Apr;24(4):563-571. doi: 10.1016/j.spinee.2023.11.010. Epub 2023 Nov 21.
7
Machine Learning to Predict Three Types of Outcomes After Traumatic Brain Injury Using Data at Admission: A Multi-Center Study for Development and Validation.机器学习使用入院时的数据预测创伤性脑损伤后的三种结局:一项用于开发和验证的多中心研究。
J Neurotrauma. 2023 Aug;40(15-16):1694-1706. doi: 10.1089/neu.2022.0515. Epub 2023 Apr 24.
8
Predictors of in-hospital length of stay among cardiac patients: A machine learning approach.心脏病人住院时间的预测因素:一种机器学习方法。
Int J Cardiol. 2019 Aug 1;288:140-147. doi: 10.1016/j.ijcard.2019.01.046. Epub 2019 Jan 19.
9
Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction?预测模型工具能否识别 ACL 重建术后阿片类药物使用时间延长的高风险患者?
Clin Orthop Relat Res. 2020 Jul;478(7):0-1618. doi: 10.1097/CORR.0000000000001251.
10
A novel explainable machine learning-based healthy ageing scale.一种新颖的基于可解释机器学习的健康老龄化量表。
BMC Med Inform Decis Mak. 2024 Oct 29;24(1):317. doi: 10.1186/s12911-024-02714-w.

本文引用的文献

1
Evaluation of factors that influenced the length of hospital stay using data mining techniques.运用数据挖掘技术评估影响住院时间的因素。
BMC Med Inform Decis Mak. 2022 Oct 29;22(1):280. doi: 10.1186/s12911-022-02027-w.
2
Prediction algorithm for ICU mortality and length of stay using machine learning.使用机器学习算法预测 ICU 死亡率和住院时间。
Sci Rep. 2022 Jul 28;12(1):12912. doi: 10.1038/s41598-022-17091-5.
3
Determinants of Prolonged Length of Hospital Stay in Patients with Severe Acute Ischemic Stroke.严重急性缺血性脑卒中患者住院时间延长的决定因素
J Clin Med. 2022 Jun 16;11(12):3457. doi: 10.3390/jcm11123457.
4
Factors Influencing Length of Stay and Discharge Destination of Patients with Hip Fracture Rehabilitating in a Private Care Setting.影响在私立护理机构中康复的髋部骨折患者住院时间和出院目的地的因素。
Geriatrics (Basel). 2022 Mar 31;7(2):44. doi: 10.3390/geriatrics7020044.
5
Predicting prolonged length of stay in hospitalized children with respiratory syncytial virus.预测呼吸道合胞病毒感染住院儿童的延长住院时间
Pediatr Res. 2022 Dec;92(6):1780-1786. doi: 10.1038/s41390-022-02008-9. Epub 2022 Mar 17.
6
Machine learning using preoperative patient factors can predict duration of surgery and length of stay for total knee arthroplasty.使用术前患者因素的机器学习可以预测全膝关节置换术的手术时间和住院时间。
Int J Med Inform. 2022 Feb;158:104670. doi: 10.1016/j.ijmedinf.2021.104670. Epub 2021 Dec 22.
7
Strategies for building robust prediction models using data unavailable at prediction time.利用预测时不可用的数据构建稳健预测模型的策略。
J Am Med Inform Assoc. 2021 Dec 28;29(1):72-79. doi: 10.1093/jamia/ocab229.
8
Association between type of anesthesia and length of hospital stay in primary unilateral total knee arthroplasty patients: a single-center retrospective study.原发性单侧全膝关节置换术患者中麻醉类型与住院时间的关系:一项单中心回顾性研究。
J Orthop Surg Res. 2021 Nov 15;16(1):671. doi: 10.1186/s13018-021-02817-4.
9
Interventions to Reduce Hospital Length of Stay in High-risk Populations: A Systematic Review.干预措施以减少高危人群的住院时间:系统评价。
JAMA Netw Open. 2021 Sep 1;4(9):e2125846. doi: 10.1001/jamanetworkopen.2021.25846.
10
A simulation-based evaluation of machine learning models for clinical decision support: application and analysis using hospital readmission.基于模拟的临床决策支持机器学习模型评估:利用医院再入院情况进行的应用与分析
NPJ Digit Med. 2021 Jun 14;4(1):98. doi: 10.1038/s41746-021-00468-7.