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解读证据:心房颤动导管消融的适应证与证据概述(综述)

Decoding the evidence: A synopsis of indications and evidence for catheter ablation in atrial fibrillation (Review).

作者信息

Obeidat Omar, Ismail Mohamed F, Abughazaleh Saeed, Al-Ani Hashim, Tarawneh Mohammad, Alhuneafat Laith, Obeidat Ali, Obeidat Abedallah, Alqudah Qusai, Daise Moh'd Alamin, Alzghoul Hamza, Al-Hammouri Mohammad, Althunibat Ward, Tong Ann, Alimohamed Mazahir

机构信息

Graduate Medical Education Program, College of Medicine, University of Central Florida, Orlando, FL 32827, USA.

Internal Medicine Residency Program, HCA Florida North Florida Hospital, Gainesville, FL 32605, USA.

出版信息

Med Int (Lond). 2024 Nov 5;5(1):1. doi: 10.3892/mi.2024.200. eCollection 2025 Jan-Feb.

DOI:10.3892/mi.2024.200
PMID:39563946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11571048/
Abstract

The present study reviews the role of catheter ablation (CA) in the management of atrial fibrillation (AF), a widespread arrhythmia associated with increased morbidity and mortality. The present review explores current indications and recent evidence supporting CA, assessing patient outcomes and identifying common complications associated with the procedure. Emphasis is placed on optimizing risk factors prior to ablation, including weight control and hypertension management, as these measures can significantly enhance post-procedural outcomes. The present review also discusses the use of antiarrhythmic and anticoagulant therapies following CA to minimize recurrence and reduce stroke risk. Additionally, the cost-effectiveness of CA is discussed, comparing its long-term economic impact with that of medical therapy alone. The present comprehensive review provides insight into best practices for AF management, supporting CA as a promising approach when integrated with targeted lifestyle modifications and pharmacological support for improved, patient-centered outcomes.

摘要

本研究回顾了导管消融术(CA)在心房颤动(AF)管理中的作用,心房颤动是一种普遍存在的心律失常,与发病率和死亡率增加相关。本综述探讨了支持CA的当前适应症和最新证据,评估了患者预后,并确定了与该手术相关的常见并发症。重点是在消融术前优化危险因素,包括体重控制和高血压管理,因为这些措施可以显著提高术后预后。本综述还讨论了CA术后使用抗心律失常和抗凝治疗以尽量减少复发和降低中风风险。此外,还讨论了CA的成本效益,将其长期经济影响与单纯药物治疗进行了比较。本全面综述深入探讨了AF管理的最佳实践,支持将CA作为一种有前景的方法,与有针对性的生活方式改变和药物支持相结合,以改善以患者为中心的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b571/11571048/8e71ed8abadb/mi-05-01-00200-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b571/11571048/8e71ed8abadb/mi-05-01-00200-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b571/11571048/8e71ed8abadb/mi-05-01-00200-g00.jpg

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本文引用的文献

1
2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2023 ACC/AHA/ACCP/HRS 指南:心房颤动的诊断与管理——美国心脏病学会/美国心脏协会联合临床实践指南委员会的报告。
Circulation. 2024 Jan 2;149(1):e1-e156. doi: 10.1161/CIR.0000000000001193. Epub 2023 Nov 30.
2
Ablation as First-line Therapy for Atrial Fibrillation.消融作为心房颤动的一线治疗方法。
Eur Cardiol. 2023 Jul 27;18:e46. doi: 10.15420/ecr.2023.04. eCollection 2023.
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Prognostic impact of catheter ablation in patients with asymptomatic atrial fibrillation.
导管消融对无症状心房颤动患者的预后影响。
PLoS One. 2022 Dec 15;17(12):e0279178. doi: 10.1371/journal.pone.0279178. eCollection 2022.
4
Catheter ablation of atrial fibrillation in heart failure with impaired systolic function: An updated meta-analysis of randomized controlled trials.收缩功能受损的心力衰竭患者房颤的导管消融:随机对照试验的最新荟萃分析
J Chin Med Assoc. 2023 Jan 1;86(1):11-18. doi: 10.1097/JCMA.0000000000000823. Epub 2022 Oct 13.
5
Comparison of catheter ablation and medical therapy for atrial fibrillation in heart failure patients: A meta-analysis of randomized controlled trials.比较心力衰竭患者心房颤动导管消融与药物治疗的疗效:一项随机对照试验的荟萃分析。
Heart Lung. 2023 Jan-Feb;57:69-74. doi: 10.1016/j.hrtlng.2022.08.012. Epub 2022 Sep 7.
6
Outcomes of catheter ablation versus antiarrhythmic therapy in patients with atrial fibrillation: a systematic review and meta-analysis.导管消融与抗心律失常治疗对心房颤动患者的疗效:一项系统评价和荟萃分析。
J Interv Card Electrophysiol. 2022 Dec;65(3):773-802. doi: 10.1007/s10840-022-01365-z. Epub 2022 Sep 3.
7
Do Elderly Patients with Atrial Fibrillation Have Comparable Ablation Outcomes Compared to Younger Ones? Evidence from Pooled Clinical Studies.老年房颤患者与年轻患者相比,消融结果是否相当?来自汇总临床研究的证据。
J Clin Med. 2022 Jul 31;11(15):4468. doi: 10.3390/jcm11154468.
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Clin Cardiol. 2022 Jul;45(7):786-793. doi: 10.1002/clc.23841. Epub 2022 May 11.
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Catheter ablation for atrial fibrillation in elderly patients: Systematic review and a meta-analysis.老年患者心房颤动的导管消融治疗:系统评价和荟萃分析。
Pacing Clin Electrophysiol. 2022 Jan;45(1):59-71. doi: 10.1111/pace.14413. Epub 2021 Dec 9.